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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Neuropsychopharmacology. 2010 Mar 31;35(8):1775–1787. doi: 10.1038/npp.2010.44

Figure 9.

Figure 9

Subchronic THC attenuates CB1 receptor binding and G-protein activity, whereas subchronic AEA produces minimal CB1 receptor adaptation. Net WIN55,212-2-stimulated [35S]GTPγS binding (top) and [3H]WIN55,212-2 binding (bottom) in THC- and AEA-treated FAAH −/− mice are expressed as a percentage of control (vehicle-treated) mice (n= 8-12 mice/group, * p<0.05 different from vehicle-treated group by one-way ANOVA with a post-hoc Dunnett’s test).