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. Author manuscript; available in PMC: 2012 Nov 25.
Published in final edited form as: Virology. 2011 Sep 28;420(2):117–124. doi: 10.1016/j.virol.2011.08.022

Table 3.

Histologic findings in marmosets inoculated with EBOV.

Animal number 28709 28705 28707 28716
Dose 103 pfu 103 pfu 10 pfu 10 pfu
Survival (days) 4 4 5 5
Liver
 Necrosis + + ++ +++
 Inclusion present present
Adrenal
 Thrombi ++ ++
 Necrosis ++ ++ +
Lung
 Thrombi ++ + ++ +
 Hemorrhage and congestion ++ + ++ +
Spleen
 Lymphoid depletion + + ++ +++
 Fibrin deposition ++ ++ ++ +++
Lymph node
 Lymphoid hyperplasia ++ ++
 Lymphoid depletion +++ + +++ +
 Neutrophilic infiltrates ++ + + +
 Hemorrhage ++ + +++ +
Urinary tract
 Glomerular tufts fibrin ++ +++ ++ ++
 Hypoxic nephrosis ++ +++ ++ +
 Hemorrhage bladder + ++ n/a

is absence of lesion;

+

is mildly;

++

moderately affected;

+++

severely affected