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. Author manuscript; available in PMC: 2015 Feb 7.
Published in final edited form as: Parasitology. 2014 Feb 20;142(0 1):S98–S107. doi: 10.1017/S0031182014000067

Table 2.

Comparing Tajima’s D of selected alleles with null distributions

P-value of Mann-Whitney test in Tajima’s D distributions Tajima’s D rejection rate

s = 0.001 s = 0.01 s = 0.1 s = 0.001 s = 0.01 s = 0.1
S§ = 5
Host selection model Standard null 0.82 0.81 0.87 3 % 3 % 4 %
Adjusted null 0.001 0.002 0.002 9 % 10 % 9 %
transmission selection model Standard null 0.61 0.05 0.47 4 % 5 % 5 %
Adjusted null 0.0001 3.4 × 10−8 2.9 × 10−5 13 % 15 % 9 %
host/transmission selection model Standard null 0.14 0.009 0.26 7 % 7 % 7 %
Adjusted null 3.7 × 10−7 2.3 × 10−10 3.9 × 10−6 14 % 15 % 15 %

S = 10
Host selection model Standard null 0.95 0.98 0.98 4 % 5 % 3 %
Adjusted null 6.9 × 10−5 0.0003 0.0004 14 % 11 % 11 %
transmission selection model Standard null 0.74 0.0001 0.17 5 % 8 % 6 %
Adjusted null 6.4 × 10−7 < 2 × 10−16 6 × 10−11 16 % 22 % 13 %
host/transmission selection model Standard null 0.02 8.9 × 10−5 0.03 9 % 15 % 8 %
Adjusted null 1.4 × 10−12 < 2 × 10−16 1.2 × 10−13 24 % 26 % 18 %

S = 50
Host selection model Standard null 1 1 1 0 % 3 % 2 %
Adjusted null 2.5 × 10−7 5.6 × 10−16 < 2 × 10−16 21 % 23 % 27 %
transmission selection model Standard null 0.22 6.9 × 10−11 0.42 4 % 25 % 6 %
Adjusted null < 2 × 10−16 < 2 × 10−16 < 2 × 10−16 45 % 63 % 40 %
host/transmission selection model Standard null 1.3 × 10−7 < 2 × 10−16 0.008 16 % 21 % 8 %
Adjusted null < 2 × 10−16 < 2 × 10−16 < 2 × 10−16 59 % 78 % 46 %
§

S is the number of segregating sites that are sampled from the site-frequency spectrum to calculate Tajima’s D.

s is selection coefficient, referring to refers to h in the host selection model, t in the transmission selection model, and h = t in the host/transmission selection model.