Figure 5.
Cellular responses of BALB/c mice to the peptides of the YF capsid and membrane protein. BALB/c mice were immunized s.c. with the human 17DD YF vaccine and assessed by ELISPOT assays for the (A) number of IFN-γ SFC for CD8-depleted splenocytes and (B) number of IFN-γ SFC for CD4-depleted splenocytes, using 15mer peptides, overlapping by 11 amino acids from the YF capsid protein (10 µg/mL). (C) number of IFN-γ SFC in CD8-depleted splenocytes and (D) number of IFN-γ SFC in CD4-depleted splenocytes, using 15mers overlapping by 11 amino acids from the YF membrane protein (10 µg/mL). Results represent the mean ± SD from three experiments.