Table 2.
Individual Quantitative fMRI Results for Language Mapping (Sentence Completion) from all Patients
| Patient 1 | Patient 2 | Patient 3 | Patient 4 | Average | |
|---|---|---|---|---|---|
| Activated voxels in respective scansa | |||||
| T2prep | |||||
| ΔS/S (%)c | 0.54 ± 0.29 | 0.87 ±0.13 | 1.14 ±0.25 | 0.64 ± 0.40 | 0.80 ± 0.23 |
| tSNRc | 57.54 ± 24.63 | 76.99 ± 24.56 | 46.77 ± 19.90 | 30.99 ± 16.23 | 53.07 ± 16.73 |
| CNRc | 31.11 ±7.09 | 67.13 ± 3.09 | 53.32 ± 4.96 | 19.87 ±6.53 | 42.86 ± 18.47 |
| EPI | |||||
| ΔS/S (%) | 0.67 ±0.12 | 0.79 ±0.14 | 1.06 ±0.21 | 0.57 ±0.18 | 0.77 ±0.18 |
| tSNR | 50.64 ± 26.67 | 76.30 ±34.15 | 46.12 ±22.27 | 31.04 ± 19.20 | 51.03 ± 16.30 |
| CNR | 34.15 ± 3.20 | 59.99 ± 4.78 | 48.89 ± 4.60 | 17.69 ± 3.54 | 40.18 ± 15.90 |
| Inferior frontal lobe including the Broca’s areab | |||||
| T2prep | |||||
| ΔS/S (%) | 0.20 ± 0.05 | 0.14 ±0.03 | 0.94 ±0.21 | 0.25 ± 0.09 | 0.38 ±0.32 |
| tSNR | 41.87 ±22.19 | 46.02 ± 26.32 | 41.78 ± 10.76 | 36.95 ±11.36 | 41.65 ± 3.21 |
| CNR | 8.41 ± 1.11 | 6.51 ±0.79 | 39.27 ±2.21 | 9.24 ± 1.02 | 15.86 ± 13.55 |
| EPI | |||||
| ΔS/S (%) | 0.05 ± 0.07 | −0.16 ±0.10 | −0.28 ± 0.29 | −0.01 ± 0.22 | −0.10 ±0.13 |
| tSNR | 40.23 ±41.05 | 36.83 ± 31.80 | 40.36 ± 32.80 | 42.34 ± 24.66 | 39.94 ± 1.98 |
| CNR | 2.01 ±2.80 | −5.89 ± 3.14 | −11.30 ±9.58 | −0.42 ± 5.42 | −3.90 ±5.14 |
| Superior temporal lobe including the Wernicke’s areab | |||||
| T2prep | |||||
| ΔS/S (%) | 0.17 ±0.05 | 0.16 ±0.05 | 0.37 ±0.11 | 0.17 ±0.11 | 0.22 ± 0.09 |
| tSNR | 77.92 ±31.90 | 91.17 ± 33.70 | 53.70 ± 28.58 | 39.99 ± 25.30 | 65.70 ± 20.02 |
| CNR | 13.25 ± 1.61 | 14.59 ± 1.81 | 19.87 ± 3.24 | 6.87 ± 2.78 | 13.64 ±4.63 |
| EPI | |||||
| ΔS/S (%) | −0.06 ± 0.04 | 0.02 ± 0.05 | 0.21 ±0.15 | 0.03 ± 0.09 | 0.05 ±0.10 |
| tSNR | 70.16 ±57.22 | 96.70 ± 56.06 | 54.20 ±31.01 | 55.42 ± 28.27 | 69.12 ± 17.12 |
| CNR | −4.21 ±2.42 | 1.93 ±2.92 | 11.38 ±4.65 | 1.56 ± 2.62 | 2.67 ± 5.59 |
Abbreviations: T2prep, T2-prepared; tSNR, temporal signal-to-noise ratio; CNR, contrast-to-noise ratio; EPI, echo planar imaging.
a
Signals averaged over all activated voxels in respective scans.
b
Signals averaged over all voxels (including voxels that did not meet the activation detection criteria described in Methodology) in the inferior frontal and superior temporal lobes, respectively. Regions of interest (ROIs) were manually drawn on the anatomical (FLAIR) image for each subject. The same ROI was used for all scans from each patient.
c
Relative signal change (ΔS/S), tSNR, and CNR are defined in Methodology.