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Synthesis of new derivatives 17a–22a (Series A) and 17b–20b (Series B). (a) (i) Boc-L-phenylalanine (17a-b and 18a-b) or N,N-dimethylglycine (for 19a–22a and 19b–20b), EDCI, DMAP; (ii) 2M HCl in diethyl ether (for 17a–18a and 21a–22a) or TFA, DCM (for 17b–18b)
