Table 3. Inflammatory Markers Before and After Smoking Cessation.
Marker | Baseline value (mean±SD) | Visit | Mean % change from baseline (95% CI) | Significance |
---|---|---|---|---|
TNF | 1.213 (0.703) pg/ml | V1 | 0 | |
V2 | −14.5 (−49.8, 45.5) | |||
V3 | −27.7 (−57.6, 23.0) | vs. V2, P<0.0115 | ||
V4 | −20.2 (−53.1, 35.9) | |||
sTNFRI | 2667.9 (1066.4) pg/ml | V1 | 0 | vs. V4, P<0.0001 |
V2 | −3.0 (−7.9, 2.2) | vs. V4, P<0.01 | ||
V3 | −3.9 (−8.7, 1.2) | vs. V4, P<0.0068 | ||
V4 | −11.6 (−16.1, −7.0) | |||
sTNFRII | 2395.1 (993.1) pg/ml | V1 | 0 | vs. V4, P<0.0048 |
V2 | −10.4 (−18.9, −1.0) | vs. V4, N.S. | ||
V3 | −3.2 (−12.3, 6.9) | vs. V4, P<0.0021 | ||
V4 | −13.7 (−21.8, −4.7) | |||
sVCAM-1 | 310.1 (119.3) ng/ml | V1 | 0 | vs. V4, P<0.0001 |
V2 | −0.6 (−8.8, 8.3) | vs. V4, P<0.0001 | ||
V3 | −4.1 (−11.9, 4.4) | vs. V4, P<0.0001 | ||
V4 | −19.5 (−26.0, −12.3) | |||
IL-6* | 3.314 (2.873) pg/ml | V1 | 0 | N.S. |
V2 | 15.0 (−10.8, 48.4) | |||
V3 | 0.7 (−21.8, 29.7) | |||
V4 | −9.6 (−29.8, 16.4) | |||
CRP* | 0.462 (0.519) mg/dL | V1 | 0 | N.S. |
V2 | −46.5 (−75.7, 18.0) | |||
V3 | −54.4 (−79.1, −0.3) | |||
V4 | −19.1 (−63.0, 76.8) |
Pairwise comparisons of visits 2 through 4 were not carried out due to non-significant (N.S.) findings.