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. 1976 Jan;17(1):247–253. doi: 10.1128/jvi.17.1.247-253.1976

Transformation of Hamster Kidney Cells by BK Papovavirus DNA

Kenneth K Takemoto 1, Malcolm A Martin 1
PMCID: PMC515409  PMID: 173887

Abstract

Supercoiled BK papovavirus DNA was shown to transform hamster kidney cells using the calcium phosphate co-precipitation technique. The transformed cells contained intranuclear T-antigen(s) and rescuable virus and produced progressively growing tumors when inoculated into hamsters. A novel finding was the production in tumor-bearing animals of antinuclear antibody, which reacted against normal, untransformed cells; in addition, tumor serum contained antibody against virus-specific T-antigen(s).

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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