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. 2007 Jun;45(6):2097. doi: 10.1128/JCM.00298-07

Arthritis Caused by Corynebacterium striatum: Spontaneous Infection?

P D J Sturm 1
PMCID: PMC1933092  PMID: 17548460

I read with interest the case report by David Scholle of arthritis caused by Corynebacterium striatum (1). The author concluded that the knee joint was most likely infected hematogenously and was, thus, a case of “a spontaneous infection of a natural joint.” However, the patient initially presented with a painful knee following trauma for which he underwent a diagnostic aspiration. This aspirate was culture negative; however, 20 days later, the knee joint was again aspirated because of persistent pain and swelling, and the aspirate now showed many neutrophils and a pure culture of Corynebacterium striatum. Although infection is a rare complication of intra-articular injection and may be even more rare after diagnostic needle aspiration of a joint, I would certainly consider this infection with C. striatum to be iatrogenic, with the introduction of this skin commensal organism into the joint during the first aspiration (2).

REFERENCES

  • 1.Scholle, D. 2007. A spontaneous joint infection with Corynebacterium striatum. J. Clin. Microbiol. 45:656-658. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.Seror, P., P. Pluvinage, F. Lecoq d'Andre, P. Benamou, and G. Attuil. 1999. Frequency of sepsis after local corticosteroid injections (an enquiry on 1 160 000 injections in rheumatological private practice in France). Rheumatology 38:1272-1274. [DOI] [PubMed] [Google Scholar]
J Clin Microbiol. 2007 Jun;45(6):2097.

Author's Reply

David Scholle 1

Dr. Sturm points out that some patients who have received steroid injections into inflamed joints have developed iatrogenic infections and proposes that this occurred in the case in question (1). Data for the incidence of infection following injection of steroid into inflamed joints have been reviewed (2). Because my patient underwent aspiration and did not receive an injection of steroid into his joint, he probably should not be included in the population of people to whom those data may apply. With regard to diagnostic arthrocentesis, I am unaware of any reports of iatrogenic septic arthritis following this procedure. The absence of any such report makes its occurrence in this case unlikely.

REFERENCES

  • 1.Scholle, D. 2007. A spontaneous joint infection with Corynebacterium striatum. J. Clin. Microbiol. 45:656-658. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.von Essen, R., and H. A. Savolainen. 1989. Bacterial infection following intra-articular injection: a brief review. Scand. J. Rheumatol. 18:7-12. [DOI] [PubMed] [Google Scholar]

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