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. 1991 Dec 25;19(24):6819–6821. doi: 10.1093/nar/19.24.6819

Requirement of protein factors and ATP for the disassembly of the spliceosome after mRNA splicing reaction.

H Sawa 1, Y Shimura 1
PMCID: PMC329315  PMID: 1762912

Abstract

Pre-mRNA splicing reaction occurs in a large ribonucleoprotein complex called the spliceosome. After the splicing reaction, the spliceosome is disassembled to release the splicing products including spliced mRNA. Here we show that protein factors in a HeLa nuclear extract or a DEAE-cellulose fraction as well as ATP are required to release the splicing products form the spliceosome in which the splicing reaction has already completed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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