Skip to main content
Biophysical Journal logoLink to Biophysical Journal
. 1986 Jan;49(1):91–94. doi: 10.1016/S0006-3495(86)83605-0

Structural Analysis of Drug Molecules in Biological Membranes

Leo G Herbette, David W Chester, David G Rhodes
PMCID: PMC1329589  PMID: 19431663

Full text

PDF
91

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Colvin R. A., Ashavaid T. F., Herbette L. G. Structure-function studies of canine cardiac sarcolemmal membranes. I. Estimation of receptor site densities. Biochim Biophys Acta. 1985 Feb 14;812(3):601–608. doi: 10.1016/0005-2736(85)90253-6. [DOI] [PubMed] [Google Scholar]
  2. Fossheim R., Svarteng K., Mostad A., Rømming C., Shefter E., Triggle D. J. Crystal structures and pharmacological activity of calcium channel antagonists: 2,6-dimethyl-3,5-dicarbomethoxy-4-(unsubstituted, 2-methyl-, 4-methyl-, 3-nitro-, 4-nitro-, and 2,4-dinitrophenyl)-1,4-dihydropyridine. J Med Chem. 1982 Feb;25(2):126–131. doi: 10.1021/jm00344a007. [DOI] [PubMed] [Google Scholar]
  3. Herbette L. G., MacAlister T., Ashavaid T. F., Colvin R. A. Structure-function studies of canine cardiac sarcolemmal membranes. II. Structural organization of the sarcolemmal membrane as determined by electron microscopy and lamellar X-ray diffraction. Biochim Biophys Acta. 1985 Feb 14;812(3):609–623. doi: 10.1016/0005-2736(85)90254-8. [DOI] [PubMed] [Google Scholar]
  4. Herbette L., Blasie J. K., Defoor P., Fleischer S., Bick R. J., Van Winkle W. B., Tate C. A., Entman M. L. Phospholipid asymmetry in the isolated sarcoplasmic reticulum membrane. Arch Biochem Biophys. 1984 Oct;234(1):235–242. doi: 10.1016/0003-9861(84)90345-x. [DOI] [PubMed] [Google Scholar]
  5. Herbette L., Katz A. M., Sturtevant J. M. Comparisons of the interaction of propranolol and timolol with model and biological membrane systems. Mol Pharmacol. 1983 Sep;24(2):259–269. [PubMed] [Google Scholar]
  6. Janis R. A., Scriabine A. Sites of action of Ca2+ channel inhibitors. Biochem Pharmacol. 1983 Dec 1;32(23):3499–3507. doi: 10.1016/0006-2952(83)90295-2. [DOI] [PubMed] [Google Scholar]
  7. Kokubun S., Reuter H. Dihydropyridine derivatives prolong the open state of Ca channels in cultured cardiac cells. Proc Natl Acad Sci U S A. 1984 Aug;81(15):4824–4827. doi: 10.1073/pnas.81.15.4824. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Rhodes D. G., Sarmiento J. G., Herbette L. G. Kinetics of binding of membrane-active drugs to receptor sites. Diffusion-limited rates for a membrane bilayer approach of 1,4-dihydropyridine calcium channel antagonists to their active site. Mol Pharmacol. 1985 Jun;27(6):612–623. [PubMed] [Google Scholar]

Articles from Biophysical Journal are provided here courtesy of The Biophysical Society

RESOURCES