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. 1977 Oct;87(2):229–236. doi: 10.1093/genetics/87.2.229

Increased Spontaneous Mitotic Segregation in Mms-Sensitive Mutants of SACCHAROMYCES CEREVISIAE

Satya Prakash 1,2, Louise Prakash 1,2
PMCID: PMC1213736  PMID: 200524

Abstract

Methyl methanesulfonate (MMS)-sensitive mutants of Saccharomyces cerevisiae belonging to four different complementation groups, when homozygous, increase the rate of spontaneous mitotic segregation to canavanine resistance from heterozygous sensitive (canr/+) diploids by 13- to 170-fold. The mms8–1 mutant is MMS and X-ray sensitive and increases the rate of spontaneous mitotic segregation 170-fold. The mms9–1 and mms13–1 mutants are sensitive to X rays and UV, respectively, in addition to MMS, and increase the rate of spontaneous mitotic segregation by 13-fold and 85-fold, respectively. The mutant mms21–1 is sensitive to MMS, X rays and UV and increases the rate of spontaneous mitotic segregation 23-fold.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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