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. 1991 Feb;83(2):161–164.

Complications following adrenal surgery.

M K McLeod 1
PMCID: PMC2627019  PMID: 2005653

Abstract

The morbidity associated with adrenalectomy can be as high as 40% and the mortality is approximately 2% to 4%. Morbidity following adrenalectomy is associated with intraoperative injury to an adjacent or contiguous structure, postoperative infection, thromboembolism, or adrenal insufficiency. Mortality is most often associated with pulmonary emboli, sepsis, a myocardial event (myocardial infarction or arrhythmia), or as a direct result of the underlying disease for which adrenalectomy is being performed. The posterior approach to adrenalectomy is associated with less blood loss and morbidity, and is best tolerated by the patient. However, the anterior transabdominal approach offers superior access to both adrenals, as well as other pertinent abdominal and retroperitoneal sites, and structures requiring concomitant exploration.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Blichert-Toft M., Bagerskov A., Lockwood K., Hasner E. Operative treatment, surgical approach, and related complications in 195 operations upon the adrenal glands. Surg Gynecol Obstet. 1972 Aug;135(2):261–266. [PubMed] [Google Scholar]
  2. Bruining H. A., Lamberts S. W., Ong E. G., van Seyen A. J. Results of adrenalectomy with various surgical approaches in the treatment of different diseases of the adrenal glands. Surg Gynecol Obstet. 1984 Apr;158(4):367–369. [PubMed] [Google Scholar]
  3. Brunicardi F. C., Rosman P. M., Lesser K. L., Andersen D. K. Current status of adrenalectomy for Cushing's disease. Surgery. 1985 Dec;98(6):1127–1134. [PubMed] [Google Scholar]
  4. Carey L. C., Ellison E. H. Adrenalectomy: technique, errors, and pitfalls. Surg Clin North Am. 1966 Oct;46(5):1283–1292. doi: 10.1016/s0039-6109(16)38042-2. [DOI] [PubMed] [Google Scholar]
  5. Cohen K. L., Noth R. H., Pechinski T. Incidence of pituitary tumors following adrenalectomy. A long-term follow-up study of patients treated for Cushing's disease. Arch Intern Med. 1978 Apr;138(4):575–579. doi: 10.1001/archinte.138.4.575. [DOI] [PubMed] [Google Scholar]
  6. Dal Bo Zanon R., Fornasiero L., Boscaro M., Cappellato G., Fabris F., Girolami A. Increased factor VIII associated activities in Cushing's syndrome: a probable hypercoagulable state. Thromb Haemost. 1982 Apr 30;47(2):116–117. [PubMed] [Google Scholar]
  7. Egdahl R. H., Melby J. C. Recurrent Cushing's disease and intermittent functional adrenal cortical insufficiency following subtotal adrenalectomy. Ann Surg. 1967 Oct;166(4):586–595. doi: 10.1097/00000658-196710000-00007. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Gonzalez-Serva L., Glenn J. F. Adrenal surgical techniques. Urol Clin North Am. 1977 Jun;4(2):327–336. [PubMed] [Google Scholar]
  9. Hardy J. D. Surgical management of Cushing's syndrome with emphasis on adrenal autotransplantation. Ann Surg. 1978 Sep;188(3):290–307. doi: 10.1097/00000658-197809000-00004. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Hauss J., Moeller A., Bünte H. Adrenalectomy in adrenal hypertension. Cardiology. 1985;72 (Suppl 1):167–173. doi: 10.1159/000173968. [DOI] [PubMed] [Google Scholar]
  11. Hoover E. L., Weaver W. L. Recent advances in the surgical management of pheochromocytoma. J Natl Med Assoc. 1989 Jul;81(7):777–779. [PMC free article] [PubMed] [Google Scholar]
  12. Huiras C. M., Pehling G. B., Caplan R. H. Adrenal insufficiency after operative removal of apparently nonfunctioning adrenal adenomas. JAMA. 1989 Feb 10;261(6):894–898. [PubMed] [Google Scholar]
  13. Mohler J. L., Flueck J. A., McRoberts J. W. Adrenal insufficiency following unilateral adrenalectomy: a case report. J Urol. 1986 Mar;135(3):554–556. doi: 10.1016/s0022-5347(17)45734-x. [DOI] [PubMed] [Google Scholar]
  14. NELSON D. H., MEAKIN J. W., THORN G. W. ACTH-producing pituitary tumors following adrenalectomy for Cushing's syndrome. Ann Intern Med. 1960 Mar;52:560–569. doi: 10.7326/0003-4819-52-3-560. [DOI] [PubMed] [Google Scholar]
  15. Pezzulich R. A., Mannix H., Jr Immediate complications of adrenal surgery. Ann Surg. 1970 Jul;172(1):125–130. [PMC free article] [PubMed] [Google Scholar]
  16. Russell C. F., Hamberger B., van Heerden J. A., Edis A. J., Ilstrup D. M. Adrenalectomy: anterior or posterior approach? Am J Surg. 1982 Sep;144(3):322–324. doi: 10.1016/0002-9610(82)90010-1. [DOI] [PubMed] [Google Scholar]
  17. Scott H. W., Jr, Liddle G. W., Mulherin J. L., Jr, Mckenna T. J., Stroup S. L., Rhamy R. K. Surgical experience with Cushing's disease. Ann Surg. 1977 May;185(5):524–534. doi: 10.1097/00000658-197705000-00004. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Van de Water J. M., Watring W. G., Linton L. A., Murphy M., Byron R. L. Prevention of postoperative pulmonary complications. Surg Gynecol Obstet. 1972 Aug;135(2):229–233. [PubMed] [Google Scholar]

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