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American Journal of Public Health logoLink to American Journal of Public Health
. 1985 Dec;75(12):1381–1384. doi: 10.2105/ajph.75.12.1381

What participants understand about a maternal serum alpha-fetoprotein screening program.

R R Faden, A J Chwalow, E Orel-Crosby, N A Holtzman, G A Chase, C O Leonard
PMCID: PMC1646434  PMID: 2415009

Abstract

We investigated the knowledge of pregnant women participating in a maternal serum alphafetoprotein (MSAFP) screening program for the detection of neural tube defects (NTDs) in the fetus. Women participating in the screening program scored higher on two knowledge tests than a comparison group of pregnant women who were not offered screening. However, there were substantial gaps in the knowledge base of women in the program, as measured by one of the tests. Women did not misinterpret a negative test result to mean that the test had identified a potential problem with the fetus; instead, there is a suggestion that they tended to interpret a negative result too positively, as an assurance that the baby was healthy in all respects.

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