There are errors in Table 2. The HADS scores included in the ALS, COPD, ESRD, FE, SISC DIGNITY < 3 (Intact), and SISC DIGNITY ≥ 3 (Fractured) columns are incorrect. Please see the corrected Table 2 here.
Table 2. Scores on Measures of Functioning Across the Four Study Groups; and Mean Levels of Functioning by Level of Dignity (Superscript indicates ranking of functioning between groups [1 = highest, to 4 = lowest].
| LEVEL OF DISTRESS ACROSS STUDY GROUPS [Mean (SD)] | SISC DIGNITY <3 (Intact) | SISC DIGNITY ≥ 3 (Fractured) | ||||||
|---|---|---|---|---|---|---|---|---|
| ALS | COPD | ESRD | FE | p-value+ | Means (SD) | Means (SD) | p-value+ | |
| Mean Number of PDI Items Rated Problematic | 6.2 (5.2)4 | 5.6 (5.9)3 | 2.3 (3.9)1 | 3.0 (4.4)2 | < .0001 | 3.9 (4.9) | 9.2 (5.6) | < .0001 |
| ESAS-R | ||||||||
| Paina | 2.3 (2.6)4 | 3.5 (3.6)1 | 3.0 (3.2)2 | 2.7 (3.1)3 | NS | 2.8 (3.1) | 4.1 (3.6) | -.07 |
| Nauseaa | 0.5 (1.4)4 | 0.8 (1.8)2 | 1.0 (2.1)1 | 0.7 (1.6)3 | NS | .07 (1.7) | 1.0 (2.2) | NS |
| Drowsinessa | 2.1 (2.7)3 | 2.4 (2.9)2 | 2.5 (2.8)1 | 1.6 (2.4)4 | NS | 2.1 (2.7) | 3.2 (2.9) | .05 |
| Shortness of Breatha | 2.9 (3.0)2 | 6.0 (3.0)1 | 1.5 (2.3)3 | 1.1 (1.9)4 | < .0001 | 2.8 (3.2) | 3.5 (3.8) | NS |
| Anxietya | 2.4 (2.6)2 | 3.4 (3.4)1 | 1.7 (2.5)3 | 1.4 (2.3)4 | < .0001 | 2.1 (2.7) | 4.1 (3.6) | .003 |
| Fatiguea | 4.3 (2.9)1 | 4.2 (3.1)2 | 3.7 (3.1)3 | 2.6 (2.8)4 | < .0001 | 3.6 (3.0) | 6.0 (3.3) | .001 |
| Constipationa | 1.8 (2.8)1 | 1.6 (2.9)2 | 1.4 (2.6)3 | 1.8 (2.8)1 | NS | 1.5 (2.6) | 3.8 (3.7) | .0002 |
| Diarrheaa | 0.5 (1.5)3 | 0.5 (1.8)3 | 0.9 (1.9)1 | 0.7 (2.0)2 | .02 | .65 (1.8) | .80 (2.3) | NS |
| Weaknessa | 5.6 (3.3)1 | 3.5 (3.1)2 | 3.2 (3.0)3 | 2.6 (2.9)4 | < .0001 | 3.5 (3.2) | 5.8 (3.4) | .001 |
| Trouble sleepinga | 1.9 (2.6)3 | 2.4 (3.4)2 | 3.2 (3.3)1 | 1.4 (2.5)4 | .0001 | 2.2 (3.0) | 3.1 (3.6) | NS |
| Dizzinessa | 0.6 (1.3)3 | 1.5 (2.5)1 | 0.9 (1.9)2 | 0.9 (2.0)2 | .04 | .9 (2.0) | 1.2 (1.7) | NS |
| Difficulty thinkinga | 0.7 (1.5)4 | 0.9 (2.1)3 | 1.0 (2.0)2 | 1.3 (2.5)1 | NS | .9 (2.0) | 1.6 (2.4) | -.07 |
| Will to liveb | 8.4 (2.9)3 | 9.2 (2.0)1 | 8.9 (2.3)2 | 8.4 (2.6)3 | NS | 8.7 (2.4) | 8.0 (3.4) | NS |
| Appetiteb | 6.5 (3.4)4 | 7.5 (3.0)2 | 8.0 (2.5)1 | 7.3 (2.8)3 | .009 | 7.4 (2.9) | 5.7 (3.3) | .006 |
| Activityb | 4.0 (2.8)4 | 4.5 (2.7)3 | 6.0 (2.6)1 | 4.6 (2.9)2 | < .0001 | 4.9 (2.8) | 3.3 (3.5) | .01 |
| Wellbeingb | 7.3 (3.0)4 | 7.4 (2.7)3 | 7.8 (2.4)2 | 7.9 (2.6)1 | NS | 7.8 (2.5) | 4.9 (3.2) | < .0001 |
| No. ADL Dependenciese | 2.2 (2.1)2 | 0.7 (1.2)3 | 0.4 (1.0)4 | 3.3 (1.5)1 | < .0001 | 1.6 (1.8) | 2.9 (2.2) | .002 |
| Charlson comorbidityf | 2.5 (1.5)4 | 5.3 (1.9)3 | 7.8 (2.0)1 | 7.1 (1.6)2 | < .0001 | 4.6 (2.5) | 5.8 (2.7) | .045 |
| Hope Hearth Index (HHI)c | 37.4 (4.7)3 | 37.8 (5.0)2 | 39.0 (5.5)1 | 35.9 (6.0)4 | .008 | 37.8 (5.2) | 34.0 (6.1) | .0008 |
| Spirituality Belief Scaled | 44.7 (19.5)3 | 43.9 (20.1)4 | 49.3 (22.2)1 | 48.4 (19.8)2 | NS | 47.2 (20.3) | 37.8 (22.0) | .02 |
| HADSg | 5.6 (3.6)1 | 5.4(3.7)2 | 3.8 (3.1)4 | 4.6 (3.4)3 | .001 | 4.7 (3.4) | 7.5 (4.6) | < .001 |
| MSPSS Social Supporth | 74.61 (10.5)1 | 69.6 (12.0)2 | 69.4 (11.8)3 | 66.8 (12.4)4 | < .0001 | 70.2 (11.9) | 69.3 (14.0) | .01 |
+Kruskal-Wallis Comparison of Distributions
aESAS-R item; scored 0 (no problem) to 10 (very significant problem)
bESAS-R item; scored 0 (low/poor) to 10 (high/good)
cHope Hearth Index; Scored 12 (least hope) to 48 (most hope)
dSpiritual Beliefs Scale; Scored 9 (unimportant/not worthwhile/rarely) to 90 (very important/very worthwhile/always)
eThe Katz Index of Daily Basic Living; Scored 0 (independent in six functions) to 6 (dependent in six functions)
fCharlson Comorbidity Index; Number of Comorbid conditions
gHADS (depression items only); Scored 0 (normal/no depression) to 21 (severe depression)
hMSPSS (Multidimensional Scale of Perceived Social Support); Scored 12 (low social support) to 84 (high social support)
Reference
- 1.Chochinov HM, Johnston W, McClement SE, Hack TF, Dufault B, Enns M, et al. (2016) Dignity and Distress towards the End of Life across Four Non-Cancer Populations. PLoS ONE 11(1): e0147607 https://doi.org/10.1371/journal.pone.0147607. [DOI] [PMC free article] [PubMed] [Google Scholar]
