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. 1978 Feb;5(2):101–106. doi: 10.1111/j.1365-2125.1978.tb01608.x

Comparison of atenolol and oxprenolol in patients with angina or hypertension and co-existent chronic airways obstruction.

W H Perks, S S Chatterjee, R S Croxson, J M Cruickshank
PMCID: PMC1429247  PMID: 339932

Abstract

1 The effects of atenolol (50 mg and 100 mg) and oxprenolol (80 mg) on respiratory function were studied in ten patients with angina pectoris or hypertension complicated by chronic airways obstruction. 2 In patients with "fixed" airways obstruction, neither atenolol nor exprenolol significantly affected airways resistance. 3 In patients with "labile" airways obstruction, atenolol did not produce a significant increase in airways obstruction, whereas oxprenolol did. 4 Following isoprenaline challenge (1500 microgram by inhalation), atenolol permitted full bronchodilatation, whereas oxprenolol almost completely blocked the action of isoprenaline. 5 Partial agonist activity appears to be of less clinical importance than cardioselectivity.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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