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Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1986 May;45(5):431–434. doi: 10.1136/ard.45.5.431

Arthritis and antinuclear antibodies (ANA) with inherited deficiency of the sixth component of complement (C6).

E Reinitz, M Lawrence, B Diamond, H Keiser, C Alper
PMCID: PMC1001906  PMID: 3487293

Abstract

We report here the case of a woman with joint pains found to have antinuclear antibodies and undetectable serum haemolytic complement. Investigation of her and her family members showed an inherited deficiency of C6.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ginsberg B., Keiser H. A Millipore filter assay for antibodies to native DNA in sera of patients with systemic lupus erythematosus. Arthritis Rheum. 1973 Mar-Apr;16(2):199–207. doi: 10.1002/art.1780160210. [DOI] [PubMed] [Google Scholar]
  2. Glass D., Raum D., Balavitch D., Kagan E., Rabson A., Schur P. H., Alper C. A. Inherited deficiency of the sixth component of complement: a silent or null gene. J Immunol. 1978 Feb;120(2):538–541. [PubMed] [Google Scholar]
  3. Hobart M. J., Lachmann P. J. Allotypes of complement components in man. Transplant Rev. 1976;32:26–42. doi: 10.1111/j.1600-065x.1976.tb00227.x. [DOI] [PubMed] [Google Scholar]
  4. KENT J. F., FIFE E. H., Jr Precise standardization of reagents for complement fixation. Am J Trop Med Hyg. 1963 Jan;12:103–116. doi: 10.4269/ajtmh.1963.12.103. [DOI] [PubMed] [Google Scholar]
  5. Keiser H. D., Weinstein J. The detection and identification of antibodies to saline extractable nuclear antigens by counterimmunoelectrophoresis. Arthritis Rheum. 1980 Sep;23(9):1026–1035. doi: 10.1002/art.1780230910. [DOI] [PubMed] [Google Scholar]
  6. Lachmann P. J., Hobart M. J., Woo P. Combined genetic deficiency of C6 and C7 in man. Clin Exp Immunol. 1978 Aug;33(2):193–203. [PMC free article] [PubMed] [Google Scholar]
  7. Tedesco F., Silvani C. M., Agelli M., Giovanetti A. M., Bombardieri S. A lupus-like syndrome in a patient with deficiency of the sixth component of complement. Arthritis Rheum. 1981 Nov;24(11):1438–1440. doi: 10.1002/art.1780241119. [DOI] [PubMed] [Google Scholar]

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