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. 1985 May 1;100(5):1637–1640. doi: 10.1083/jcb.100.5.1637

Active maturation-promoting factor is present in mature mouse oocytes

PMCID: PMC2113872  PMID: 3886670

Abstract

Cytoplasmic extracts of meiotically mature mouse oocytes were injected into immature Xenopus laevis oocytes, which underwent germinal vesicle breakdown within 2 h. Germinal vesicle breakdown was not inhibited by incubation of the Xenopus oocytes in cycloheximide (20 micrograms/ml). Identically prepared extracts of meiotically immature mouse oocytes, arrested at the germinal vesicle stage by dibutyryl cyclic AMP (100 micrograms/ml), did not induce germinal vesicle breakdown in Xenopus oocytes. The results show that maturation-promoting factor activity appears during the course of oocyte maturation in the mouse.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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