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. 1985 Feb;142(2):197–202.

Current Trends in Antifertility Vaccine Research

Donald E Moore 1,2,3, Dana C Covey 1,2,3, Kelvin D O'Brien 1,2,3
PMCID: PMC1305978  PMID: 3892913

Abstract

We review the major advances that have recently occurred in the area of antifertility vaccines by examining the immunogenic potential of gamete, embryonic and placental antigens. In human trials using β-human chorionic gonadotropin coupled with tetanus toxoid as the immunogen, the major problems with antifertility vaccines relate to specificity and maintaining an adequate antibody titer to disrupt gestation. Possible complications include cross-reaction with other body tissues, immune complex deposition, cytotoxicity, impaired immunologic tumor surveillance and nonreversibility.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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