Abstract
A mixture was composed consisting of PPD, Varidase, Trychophyton-antigen, mumps-antigen and Candida-antigen. The reactivity to each antigen was tested and the response to the cocktail was found to reflect the sum of the effects of the anamnestic response to each antigen separately with a maximum of about the PHA-responsiveness. A group of twenty-five individuals showed an anamnestic response to at least two of the components of the antigen mixture. The cocktail as described may be useful in testing the cellular anamnestic response to antigens in patients who have a very low number of lymphocytes in their peripheral blood, such as patients with immune deficiencies and thermal injuries.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Mills J. A. The immunologic significance of antigen induced lymphocyte transformation in vitro. J Immunol. 1966 Aug;97(2):239–247. [PubMed] [Google Scholar]
- Oppenheim J. J., Wolstencroft R. A., Gell P. G. Delayed hypersensitivity in the guinea-pig to a protein-hapten conjugate and its relationship to in vitro transformation of lymph node, spleen, thymus and peripheral blood lymphocytes. Immunology. 1967 Jan;12(1):89–102. [PMC free article] [PubMed] [Google Scholar]
- Schellekens P. T., Eijsvoogel V. P. Lymphocyte transformation in vitro. I. Tissue culture conditions and quantitative measurements. Clin Exp Immunol. 1968 Jul;3(6):571–584. [PMC free article] [PubMed] [Google Scholar]
- Schellekens P. T., Eijsvoogel V. P. Lymphocyte transformation in vitro. IV. Recruitment in antigen-stimulated cultures. Clin Exp Immunol. 1971 Feb;8(2):187–194. [PMC free article] [PubMed] [Google Scholar]