Abstract
At least two different types of plaque-forming cells (PFC) participating in the immune response of mice to sheep red blood cells (SRBC) are identified. This is demonstrated by (a) two PFC-peaks appearing at different times in response to the same low dose of antigen; (b) the morphology of the PFC in each of the two peaks is different; (c) the PFC in each peak respond differently to the suppressive effect of anti-SRBC serum.
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- Plotz P. H., Talal N., Asofsky R. Assignment of direct and facilitated hemolytic plaques in mice to specific immunoglobulin classes. J Immunol. 1968 Apr;100(4):744–751. [PubMed] [Google Scholar]
- Ryder R. J., Schwartz R. S. Immunosuppression by antibody: localization of site of action. J Immunol. 1969 Nov;103(5):970–978. [PubMed] [Google Scholar]
- STERZL J., MANDEL L. ESTIMATION OF THE INDUCTIVE PHASE OF ANTIBODY FORMATION BY PLAQUE TECHNIQUE. Folia Microbiol (Praha) 1964 May;14:173–176. doi: 10.1007/BF02874003. [DOI] [PubMed] [Google Scholar]
- Wigzell H. Antibody synthesis at the cellular level: some studies on natural anti-sheep red cell antibodies in the mouse. J Immunol. 1966 Nov;97(5):608–611. [PubMed] [Google Scholar]
- Wigzell H., Möller G., Andersson B. Studies at the cellular level of the 19S immune response. Acta Pathol Microbiol Scand. 1966;66(4):530–540. doi: 10.1111/apm.1966.66.4.530. [DOI] [PubMed] [Google Scholar]
- Wortis H. H., Taylor R. B., Dresser D. W. Antibody production studied by means of the LHG assay. I. The splenic response of CBA mice to sheep erythrocytes. Immunology. 1966 Dec;11(6):603–616. [PMC free article] [PubMed] [Google Scholar]