Abstract
Specific alloantibody admixed with a grafted murine lymphoma is suppressive of the graft in mice of the inbred strain native to the tumor. Suppressive capacity of the host is obviated in mice given 500 R whole body irradiation before tumor inoculation but is restored when normal peritoneal macrophages are admixed with the tumor-antibody inoculum. Other normal cell types admixed with the tumor-antibody inoculum are not effective in restoring suppressive capacity.
Full Text
The Full Text of this article is available as a PDF (298.4 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Perlmann P., Holm G. Cytotoxic effects of lymphoid cells in vitro. Adv Immunol. 1969;11:117–193. doi: 10.1016/s0065-2776(08)60479-4. [DOI] [PubMed] [Google Scholar]
- Shin H. S., Kaliss N., Borenstein D. Antibody-mediated suppression of grafted lymphoma cells. I. Participation of a host factor(s) other than complement. Proc Soc Exp Biol Med. 1972 Feb;139(2):684–689. doi: 10.3181/00379727-139-36216. [DOI] [PubMed] [Google Scholar]