Abstract
Postictal values of prolactin, LH and FSH have been recorded in patients with both generalised tonic-clonic and partial seizures. Elevations of prolactin and LH were seen immediately and at 20 minutes in males and females with generalised attacks. At sixty minutes values for prolactin had fallen to baseline levels, but LH remained elevated. FSH values were increased in females only, at twenty and sixty minutes. Following partial seizures prolactin was elevated, especially with complex partial seizures, at twenty minutes. These results are discussed in the light of known electrophysiological mechanisms relating to partial seizures, and clinical guidelines for the use of neurohormonal tests in the evaluation of seizures are suggested.
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Selected References
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- Abbott R. J., Browning M. C., Davidson D. L. Serum prolactin and cortisol concentrations after grand mal seizures. J Neurol Neurosurg Psychiatry. 1980 Feb;43(2):163–167. doi: 10.1136/jnnp.43.2.163. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Arató M., Erdós A., Kurcz M., Vermes I., Fekete M. Studies on the prolactin response induced by electroconvulsive therapy in schizophrenics. Acta Psychiatr Scand. 1980 Mar;61(3):239–244. doi: 10.1111/j.1600-0447.1980.tb00873.x. [DOI] [PubMed] [Google Scholar]
- Clemens J. A., Shaar C. J., Kleber J. W., Tandy W. A. Reciprocal control by the preoptic area of LH and prolactin. Exp Brain Res. 1971;12(3):250–253. doi: 10.1007/BF00237917. [DOI] [PubMed] [Google Scholar]
- JASPER H. H. SOME PHYSIOLOGICAL MECHANISMS INVOLVED IN EPILEPTIC AUTOMATISMS. Epilepsia. 1964 Mar;5:1–20. doi: 10.1111/j.1528-1157.1964.tb04341.x. [DOI] [PubMed] [Google Scholar]
- Meldrum B. S., Horton R. W., Bloom S. R., Butler J., Keenan J. Endocrine factors and glucose metabolism during prolonged seizures in baboons. Epilepsia. 1979 Oct;20(5):527–533. doi: 10.1111/j.1528-1157.1979.tb04835.x. [DOI] [PubMed] [Google Scholar]
- Noel G. L., Suh H. K., Stone J. G., Frantz A. G. Human prolactin and growth hormone release during surgery and other conditions of stress. J Clin Endocrinol Metab. 1972 Dec;35(6):840–851. doi: 10.1210/jcem-35-6-840. [DOI] [PubMed] [Google Scholar]
- O'Dea J. P., Gould D., Hallberg M., Wieland R. G. Prolactin changes during electroconvulsive therapy. Am J Psychiatry. 1978 May;135(5):609–611. doi: 10.1176/ajp.135.5.609. [DOI] [PubMed] [Google Scholar]
- Ohman R., Walinder J., Balldin J., Wallin L. Prolactin response to electroconvulsive therapy. Lancet. 1976 Oct 30;2(7992):936–937. doi: 10.1016/s0140-6736(76)90895-3. [DOI] [PubMed] [Google Scholar]
- Ryan R. J., Swanson D. W., Faiman C., Mayberry W. E., Spadoni A. J. Effects of convulsive electroshock on serum concentrations of follicle stimulating hormone, luteinizing hormone, thyroid stimulating hormone and growth hormone in man,. J Clin Endocrinol Metab. 1970 Jan;30(1):51–58. doi: 10.1210/jcem-30-1-51. [DOI] [PubMed] [Google Scholar]
- Thorner M. O., Login I. S. Prolactin secretion as an index of brain dopaminergic function. Adv Biochem Psychopharmacol. 1981;28:503–520. [PubMed] [Google Scholar]
- Trimble M. R. Serum prolactin in epilepsy and hysteria. Br Med J. 1978 Dec 16;2(6153):1682–1682. doi: 10.1136/bmj.2.6153.1682. [DOI] [PMC free article] [PubMed] [Google Scholar]