Skip to main content
The British Journal of Ophthalmology logoLink to The British Journal of Ophthalmology
. 1978 May;62(5):287–291. doi: 10.1136/bjo.62.5.287

Long-term hypotensive effect of atenolol 4% eyedrops.

R F Brenkman
PMCID: PMC1043215  PMID: 656355

Abstract

The effect of long-term application of 4% atenolol eye drops has been studied in patients with either glaucoma or ocular hypertension. In some patients who show a good initial response the ocular hypotensive effect gradually wears off with long-term use. This pattern of response appears to be more frequent in patients with pretreatment intraocular pressure of 25 mmHg, or greater. In combination with atenolol miotics or adrenaline show an additive effect.

Full text

PDF
287

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Elliot M. J., Cullen P. M., Phillips C. I. Ocular hypotensive effect of atenolol (Tenormin, I.C.I.). A new beta-adrenergic blocker. Br J Ophthalmol. 1975 Jun;59(6):296–300. doi: 10.1136/bjo.59.6.296. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Langham M. E. Proceedings: Adrenergic tachyphylaxis in animal and human eyes. Exp Eye Res. 1975 Feb;20(2):174–175. doi: 10.1016/0014-4835(75)90157-8. [DOI] [PubMed] [Google Scholar]
  3. Macdonald M. J., Cullen P. M., Phillips C. I. Atenolol versus propranolol. A comparison of ocular hypotensive effect of an oral dose. Br J Ophthalmol. 1976 Nov;60(11):789–791. doi: 10.1136/bjo.60.11.789. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Paterson G. D., Paterson G. A comparison of the ocular hypotensive actions of salbutamol and adrenaline in chronic simple glaucoma. Postgrad Med J. 1971 Mar;47(Suppl):122–124. [PubMed] [Google Scholar]
  5. Phillips C. I., Howitt G., Rowlands D. J. Propranolol as ocular hypotensive agent. Br J Ophthalmol. 1967 Apr;51(4):222–226. doi: 10.1136/bjo.51.4.222. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Rahi A. H., Chapman C. M., Garner A., Wright P. Pathology of practolol-induced ocular toxicity. Br J Ophthalmol. 1976 May;60(5):312–323. doi: 10.1136/bjo.60.5.312. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Vale J., Phillips C. I. Effect of DL- and D-propranolol on oscular tension in rabbits and patients. Exp Eye Res. 1970 Jan;9(1):82–90. doi: 10.1016/s0014-4835(70)80061-6. [DOI] [PubMed] [Google Scholar]
  8. Vale J., Phillips C. I. Practolol (Eraldin) eye drops as an ocular hypotensive agent. Br J Ophthalmol. 1973 Mar;57(3):210–214. doi: 10.1136/bjo.57.3.210. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Wettrell K., Pandolfi M. Effect of oral administration of various beta-blocking agents on the intraocular pressure in healthy volunteers. Exp Eye Res. 1975 Nov;21(5):451–456. doi: 10.1016/0014-4835(75)90126-8. [DOI] [PubMed] [Google Scholar]

Articles from The British Journal of Ophthalmology are provided here courtesy of BMJ Publishing Group

RESOURCES