Abstract
Left ventricular echocardiographic parameters in cats were recorded, measured and analyzed to study the effects of a combination of xylazine and sodium pentobarbital on left ventricular function. The depressant effects of a combination of xylazine and sodium pentobarbital on the left ventricular dimension at end diastole, the percent change in minor diameter and the velocity of circumferential fibre shortening were compared to echocardiographic values of unanesthetized cats. No change in heart rate was noted. Stroke volume and cardiac output were depressed.
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Selected References
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- Allen D. G. Echocardiographic study of the anesthetized cat. Can J Comp Med. 1982 Apr;46(2):115–122. [PMC free article] [PubMed] [Google Scholar]
- Baker M. L., Dalrymple G. V. Biological effects of diagnostic ultrasound: a review. Radiology. 1978 Feb;126(2):479–483. doi: 10.1148/126.2.479. [DOI] [PubMed] [Google Scholar]
- Cohen R. B., Tilley L. P. Cardiac arrhythmias in the anesthetized patient. Vet Clin North Am Small Anim Pract. 1979 May;9(2):155–167. doi: 10.1016/s0195-5616(79)50027-8. [DOI] [PubMed] [Google Scholar]
- Hirota Y., Suwa M., Hori K., Takatsu T. Dynamic echoventriculography. Noninvasive assessment of effects of nitroglycerin, phenylephrine, isoproterenol, and propranolol on the human cardiovascular system. Jpn Heart J. 1978 Sep;19(5):719–731. doi: 10.1536/ihj.19.719. [DOI] [PubMed] [Google Scholar]
- Merin R. G. Effect of anesthetics on the heart. Surg Clin North Am. 1975 Aug;55(4):759–774. doi: 10.1016/s0039-6109(16)40679-1. [DOI] [PubMed] [Google Scholar]
- Moye R. J., Pailet A., Smith M. W., Jr Clinical use of xylazine in dogs and cats. Vet Med Small Anim Clin. 1973 Mar;68(3):236–passimassim. [PubMed] [Google Scholar]
- Muir W. W. Anesthesia and the heart. J Am Vet Med Assoc. 1977 Jul 1;171(1):92–98. [PubMed] [Google Scholar]
- Muir W. W., Piper F. S. Effect of xylazine on indices of myocardial contractility in the dog. Am J Vet Res. 1977 Jul;38(7):931–934. [PubMed] [Google Scholar]
- Newkirk H. L., Miles D. G. Xylazine as a sedative-analgesic for dogs and cats. Mod Vet Pract. 1974 Sep;55(9):677–passim. [PubMed] [Google Scholar]
- Pipers F. S., Hamlin R. L. Clinical use of echocardiography in the domestic cat. J Am Vet Med Assoc. 1980 Jan 1;176(1):57–61. [PubMed] [Google Scholar]
- Pipers F. S., Reef V., Hamlin R. L. Echocardiography in the domestic cat. Am J Vet Res. 1979 Jun;40(6):882–886. [PubMed] [Google Scholar]
- Pratila M. G., Pratilas V. Anesthetic agents and cardiac electromechanical activity. Anesthesiology. 1978 Nov;49(5):338–360. doi: 10.1097/00000542-197811000-00007. [DOI] [PubMed] [Google Scholar]
- Purohit R. C., Mysinger P. W., Redding R. W. Effects of xylazine and ketamine hydrochloride on the electroencephalogram and the electrocardiogram in the horse. Am J Vet Res. 1981 Apr;42(4):615–619. [PubMed] [Google Scholar]
- Quinones M. A., Gaasch W. H., Alexander J. K. Echocardiographic assessment of left ventricular function with special reference to normalized velocities. Circulation. 1974 Jul;50(1):42–51. doi: 10.1161/01.cir.50.1.42. [DOI] [PubMed] [Google Scholar]
- Quinones M. A., Gaasch W. H., Alexander J. K. Influence of acute changes in preload, afterload, contractile state and heart rate on ejection and isovolumic indices of myocardial contractility in man. Circulation. 1976 Feb;53(2):293–302. doi: 10.1161/01.cir.53.2.293. [DOI] [PubMed] [Google Scholar]
- Urthaler F., Krames B. L., James T. N. Selective effects of pentobarbital on automaticity and conduction in the intact canine heart. Cardiovasc Res. 1974 Jan;8(1):46–57. doi: 10.1093/cvr/8.1.46. [DOI] [PubMed] [Google Scholar]
- Vatner S. F., Braunwald E. Cardiovascular control mechanisms in the conscious state. N Engl J Med. 1975 Nov 6;293(19):970–976. doi: 10.1056/NEJM197511062931906. [DOI] [PubMed] [Google Scholar]