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British Journal of Clinical Pharmacology logoLink to British Journal of Clinical Pharmacology
. 1981 Apr;11(4):383–384. doi: 10.1111/j.1365-2125.1981.tb01136.x

Sodium cromoglycate: spincaps or metered dose aerosol.

R A Robson, B J Taylor, B Taylor
PMCID: PMC1401659  PMID: 6789851

Abstract

1 Sodium cromoglycate administered as a dry powder inhalation (20 mg/dose) via the Spinhaler was compared with a metered dose aerosol (2 mg/dose) in an eight week double dummy double blind crossover trial in 29 asthmatic children. 2 The powder formulation was associated with significantly less symptoms (night wheeze, night cough, day wheeze, day cough, activity) and bronchodilator intake; and significantly greater weight gain than aerosol therapy. There were no significant differences in morning or evening peak flow measurements on the two treatments. 3 The powder may be more effectively inhaled than the aerosol or the dose of the aerosol may not be large enough.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Chambers S., Dunbar J., Taylor B. Inhaled powder compared with aerosol administration of fenoterol in asthmatic children. Arch Dis Child. 1980 Jan;55(1):73–74. doi: 10.1136/adc.55.1.73. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Lenney W., Milner A. D. Nebulised sodium cromoglycate in the preschool wheezy child. Arch Dis Child. 1978 Jun;53(6):474–476. doi: 10.1136/adc.53.6.474. [DOI] [PMC free article] [PubMed] [Google Scholar]
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