Abstract
A unique case of pachydermoperiostosis, multiple epiphyseal dysplasia, and secondary osteoarthritis is described. An additional interesting feature was the presence of acroosteolysis of the distal phalanges of fingers and toes. Scintigraphic, thermographic, plethysmographic, and capillaroscopic studies suggested increased blood flow through clubbed fingers, raising the possibility that this may play a role in the pathogenesis of pachydermoperiostosis.
Full text
PDF




Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BARRIE H., CARTER C., SUTCLIFFE J. Multiple epiphysial dysplasia. Br Med J. 1958 Jul 19;2(5089):133–137. doi: 10.1136/bmj.2.5089.133. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Challoner A. V., Ramsay C. A. A photoelectric plethysmograph for the measurement of cutaneous blood flow. Phys Med Biol. 1974 May;19(3):317–328. doi: 10.1088/0031-9155/19/3/003. [DOI] [PubMed] [Google Scholar]
- Gibson T., Highton J. Multiple epiphyseal dysplasia: a family study. Rheumatol Rehabil. 1979 Nov;18(4):239–242. doi: 10.1093/rheumatology/18.4.239. [DOI] [PubMed] [Google Scholar]
- HOLLING H. E., BRODEY R. S., BOLAND H. C. Pulmonary hypertrophic osteoarthropathy. Lancet. 1961 Dec 9;2(7215):1269–1274. doi: 10.1016/s0140-6736(61)91138-2. [DOI] [PubMed] [Google Scholar]
- Hedayati H., Barmada R., Skosey J. L. Acrolysis in pachydermoperiostosis. Primary or idiopathic hypertrophic osteoarthropathy. Arch Intern Med. 1980 Aug;140(8):1087–1088. doi: 10.1001/archinte.140.8.1087. [DOI] [PubMed] [Google Scholar]
- Jajić I., Pećina M., Krstulović B., Kovacević D., Pavicić F., Spaventi S. Primary hypertrophic osteoarthropathy (PHO) and changes in the joints. Clinical, X-ray, scintigraphic, arteriographic and histologic examination of 19 patients. Scand J Rheumatol. 1980;9(2):89–96. doi: 10.3109/03009748009098136. [DOI] [PubMed] [Google Scholar]
- LEEDS N. E. Epiphysial dysplasia multiplex. Am J Roentgenol Radium Ther Nucl Med. 1960 Sep;84:506–510. [PubMed] [Google Scholar]
- Lauter S. A., Vasey F. B., Hüttner I., Osterland C. K. Pachydermoperiostosis: studies on the synovium. J Rheumatol. 1978 Spring;5(1):85–95. [PubMed] [Google Scholar]
- Murphy M. C., Shine I. B., Stevens D. B. Multiple epiphyseal dysplasia. Report of a pedigree. J Bone Joint Surg Am. 1973 Jun;55(4):814–820. [PubMed] [Google Scholar]
- Rosenthall L., Kirsh J. Observations of radionuclide imaging in hypertrophic pulmonary osteoarthropathy. Radiology. 1976 Aug;120(2):359–362. doi: 10.1148/120.2.359. [DOI] [PubMed] [Google Scholar]
- Rutherford R. B., Rhodes B. A., Wagner H. N., Jr The distribution of extremity blood flow before and after vagectomy in a patient with hypertrophic pulmonary osteoarthropathy. Dis Chest. 1969 Jul;56(1):19–23. doi: 10.1378/chest.56.1.19. [DOI] [PubMed] [Google Scholar]
- Schumacher H. R., Jr Articular manifestations of hypertrophic pulmonary osteoarthropathy in bronchogenic carcinoma. Arthritis Rheum. 1976 May-Jun;19(3):629–636. doi: 10.1002/art.1780190317. [DOI] [PubMed] [Google Scholar]
- VOGL A., BLUMENFELD S., GUTNER L. B. Diagnostic significance of pulmonary hypertrophic osteoarthropathy. Am J Med. 1955 Jan;18(1):51–65. doi: 10.1016/0002-9343(55)90205-9. [DOI] [PubMed] [Google Scholar]
- VOGL A., GOLDFISCHER S. Pachydermoperiostosis. Primary or idiopathic hypertrophic osteoarthropathy. Am J Med. 1962 Aug;33:166–187. doi: 10.1016/0002-9343(62)90016-5. [DOI] [PubMed] [Google Scholar]







