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. 1980 Jan 1;151(1):246–251. doi: 10.1084/jem.151.1.246

Suppression of T cells specific for the nonthymic parental H-2 haplotype in thymus-grafted chimeras

PMCID: PMC2185764  PMID: 6965308

Abstract

The mechanism of restriction of T-cell specificity by the genotype of the thymus in allogeneic and semiallogeneic chimeras was investigated. Lack of induction of delayed-type hypersensitivity (DTH) directed against antigen in association with the nonthymic parental haplotype in naive cells adoptively transferred into chimeras suggests the existence of an in vivo suppressive mechanism. However, it was not possible to suppress the expression of DTH in sensitized cells transferred into chimeras, or to transfer this suppression to normal naive recipients.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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