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. 1981 Jun;35(2):91–97. doi: 10.1136/jech.35.2.91

The Paris Cardiovascular Risk Factor Prevention Trial. Effects of two years of intervention in a population of young men.

F Cambien, J L Richard, P Ducimetiere, J M Warnet, J Kahn
PMCID: PMC1052130  PMID: 7299342

Abstract

The Paris Cardiovascular Risk Factor Prevention Trial was designed to determine whether individualised intervention could induce a reduction in the coronary risk factor levels in young men. Three thousand three hundred and thirty-six men aged 25 to 35, working in the 160 sections of a large Parisian administration, were examined. The section were randomly allocated to a control and an intervention group. Advice concerning diet, cigarette smoking, and physical activity was provided repeatedly to the subjects in the intervention group. Two years after the first intervention, the first 1292 subjects who entered the study, whether from the intervention or the control group, were recalled; 86% of the intervention group and 84% of the control group responded. The changes in weight, blood pressure, and cigarette smoking in the intervention group, corrected for changes in the control group, were respectively -0.4 kg (p = 0.06), -1.4 mm Hg (p less than 0.05), and -1.2 cigarettes (p less than 0.01). There was no difference between the two groups in serum cholesterol change. Most of these results concerning young men are in agreement with recently reported results of community intervention programmes in middle-aged men.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Cohen J. D., Bartsch G. E. A comparison between carboxyhemoglobin and serum thiocyanate determinations as indicators of cigarette smoking. Am J Public Health. 1980 Mar;70(3):284–286. doi: 10.2105/ajph.70.3.284. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Ducimetière P., Kritsikis S., Richard J. L., Pèquignot G. Variation de poids des fumeurs d'âge moyen après modifications de leur consommation de tabac. Rev Epidemiol Sante Publique. 1978;26(2):195–198. [PubMed] [Google Scholar]
  3. Farquhar J. W., Maccoby N., Wood P. D., Alexander J. K., Breitrose H., Brown B. W., Jr, Haskell W. L., McAlister A. L., Meyer A. J., Nash J. D. Community education for cardiovascular health. Lancet. 1977 Jun 4;1(8023):1192–1195. doi: 10.1016/s0140-6736(77)92727-1. [DOI] [PubMed] [Google Scholar]
  4. Farquhar J. W. The community-based model of life style intervention trials. Am J Epidemiol. 1978 Aug;108(2):103–111. doi: 10.1093/oxfordjournals.aje.a112593. [DOI] [PubMed] [Google Scholar]
  5. Kornitzer M., De Backer G., Dramaix M., Thilly C. The Belgian heart disease prevention project. Modification of the coronary risk profile in an industrial population. Circulation. 1980 Jan;61(1):18–25. doi: 10.1161/01.cir.61.1.18. [DOI] [PubMed] [Google Scholar]
  6. Puska P., Koskela K., Pakarinen H., Puumalainen P., Soininen V., Tuomilehto J. The North Karelia Project: a programme for community control of cardiovascular diseases. Scand J Soc Med. 1976;4(2):57–60. [PubMed] [Google Scholar]
  7. Puska P., Tuomilehto J., Salonen J., Neittaanmäki L., Maki J., Virtamo J., Nissinen A., Koskela K., Takalo T. Changes in coronary risk factors during comprehensive five-year community programme to control cardiovascular diseases (North Karelia project). Br Med J. 1979 Nov 10;2(6199):1173–1178. doi: 10.1136/bmj.2.6199.1173. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Richard J. L., Ducimetière P., Bonnaud G., Claude J. R., Lellouch J., Schwartz D., Di Mattéo J. Incidence et évaluation du risque de maladie coronarienne: l'étude prospective parisienne. Arch Mal Coeur Vaiss. 1977 May;70(5):531–540. [PubMed] [Google Scholar]
  9. Rose G., Heller R. F., Pedoe H. T., Christie D. G. Heart disease prevention project: a randomised controlled trial in industry. Br Med J. 1980 Mar 15;280(6216):747–751. doi: 10.1136/bmj.280.6216.747. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Vogt T. M., Selvin S., Hulley S. B. Comparison of biochemical and questionnaire estimates of tobacco exposure. Prev Med. 1979 Jan;8(1):23–33. doi: 10.1016/0091-7435(79)90026-4. [DOI] [PubMed] [Google Scholar]
  11. Wilhelmsen L., Tibblin G., Werkö L. A primary preventive study of Gothenburg, Sweden. Prev Med. 1972 Mar;1(1):153–160. doi: 10.1016/0091-7435(72)90082-5. [DOI] [PubMed] [Google Scholar]

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