Abstract
A detailed casenote review was performed on 55 patients registered with testicular non-seminomatous germ cell tumours (NSGCT) between 1983 and 1988 under the Scottish Cancer Registration Scheme and who had died by 1992. Details of all aspects of clinical management relating to their NSGCT and death details were extracted and summarised. An assessment was made on whether the patients' management had been optimal. An analysis of 5 year survival rates by the five Scottish oncology centres demonstrated significant differences between centres (range 70.4-94.2; chi 2 = 14.46, d.f. = 4, P = 0.006). Some patients in all centres were assessed as having received suboptimal treatment, but two centres performed less well than the other three. There is a suggestion that the number of patients treated suboptimally decreases with increasing number of patients seen, but this does not reach statistical significance.
Full text
PDF




Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Clarke K., Howard G. C., Elia M. H., Hutcheon A. W., Kaye S. B., Windsor P. M., Yosef H. M. Referral patterns within Scotland to specialist oncology centres for patients with testicular germ cell tumours. The Scottish Radiological Society and the Scottish Standing Committee of the Royal College of Radiologists. Br J Cancer. 1995 Nov;72(5):1300–1302. doi: 10.1038/bjc.1995.504. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ewing R., Hetherington J. W., Jones W. G., Williams R. E. Surgical salvage of advanced testicular tumours. Br J Urol. 1987 Jan;59(1):76–80. doi: 10.1111/j.1464-410x.1987.tb04585.x. [DOI] [PubMed] [Google Scholar]
- Harding M. J., Paul J., Gillis C. R., Kaye S. B. Management of malignant teratoma: does referral to a specialist unit matter? Lancet. 1993 Apr 17;341(8851):999–1002. doi: 10.1016/0140-6736(93)91082-w. [DOI] [PubMed] [Google Scholar]
- Hendry W. F., Goldstraw P., Peckham M. J. The role of surgery in the combined management of metastases from malignant teratomas of testis. Br J Urol. 1987 Apr;59(4):358–358. doi: 10.1111/j.1464-410x.1987.tb04649.x. [DOI] [PubMed] [Google Scholar]
- Howard G. C., Clarke K., Elia M. H., Hutcheon A. W., Kaye S. B., Windsor P. M. A Scottish national audit of current patterns of management for patients with testicular non-seminomatous germ-cell tumours. The Scottish Radiological Society and the Scottish Committee of the Royal College of Radiologists. Br J Cancer. 1995 Nov;72(5):1303–1306. doi: 10.1038/bjc.1995.505. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mead G. M., Stenning S. P., Parkinson M. C., Horwich A., Fossa S. D., Wilkinson P. M., Kaye S. B., Newlands E. S., Cook P. A. The Second Medical Research Council study of prognostic factors in nonseminomatous germ cell tumors. Medical Research Council Testicular Tumour Working Party. J Clin Oncol. 1992 Jan;10(1):85–94. doi: 10.1200/JCO.1992.10.1.85. [DOI] [PubMed] [Google Scholar]
- Peckham M. J., McElwain T. J., Barrett A., Hendry W. F. Combined management of malignant teratoma of the testis. Lancet. 1979 Aug 11;2(8137):267–270. doi: 10.1016/s0140-6736(79)90288-5. [DOI] [PubMed] [Google Scholar]
- Stiller C. A. Centralised treatment, entry to trials and survival. Br J Cancer. 1994 Aug;70(2):352–362. doi: 10.1038/bjc.1994.306. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Whillis D., Coleman R. E., Lessells A. M., Hargreave T. B., Cornbleet M. A., Howard G. C. Surgery following chemotherapy for metastatic testicular teratoma. Br J Urol. 1991 Sep;68(3):292–295. doi: 10.1111/j.1464-410x.1991.tb15326.x. [DOI] [PubMed] [Google Scholar]