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. 1977 Aug;33(2):269–273.

Stimulation and inhibition of macrophages prior to immunization with a hapten-carrier conjugate.

P J Neveu
PMCID: PMC1445339  PMID: 75840

Abstract

Delayed hypersensitivity reactions and antibody-mediated reactions to the carrier and to the hapten have been studied in animals treated with BCG or/and trypan blue before immunization with a hapten-carrier complex. The results show that it is possible to induce, with BCG, at the beginning of the response, an antigenic competition between hapten and carrier moieties of the antigen molecule. Macrophages which modulate the response to the hapten-carrier complex by acting both on T cells involved in cellular immunity and those involved in antibody synthesis, appear to be the target of antigenic competition.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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