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. 1979 Jan 13;1(6156):82–84. doi: 10.1136/bmj.1.6156.82

Detection of deep venous thrombosis by scanning of 99mtechnetium-labelled red-cell venous pool.

W Beswick, R Chmiel, R Booth, I Vellar, E Gilford, C N Chesterman
PMCID: PMC1598210  PMID: 761002

Abstract

A comparative study of 32 patients with suspected deep venous thrombosis was carried out using blood-pool radionuclide scanning and conventional x-ray phlebography. Results of the two methods showed close agreement, the sensitivity (positive correlation) of the scan being 100% and its specificity 89%. We conclude that a patient's red cells labelled with 99mtechnetium (99mTc) provide an excellent medium for this type of scanning. The technique has particular advantages in visualising the whole venous system, giving a persisting image, and obviating the need to inject into a vein of the affected limb. In view of the inherent disadvantages of contrast phlebography, 99mTc-red-cell scanning is clearly an acceptable alternative.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Albrechtsson U., Olsson C. G. Thrombotic side-effects of lower-limb phlebography. Lancet. 1976 Apr 3;1(7962):723–724. doi: 10.1016/s0140-6736(76)93094-4. [DOI] [PubMed] [Google Scholar]
  2. Bettmann M. A., Paulin S. Leg phlebography: the incidence, nature and modification of undesirable side effects. Radiology. 1977 Jan;122(1):101–104. doi: 10.1148/122.1.101. [DOI] [PubMed] [Google Scholar]
  3. Ennis J. T., Elmes R. J. Radionuclide venography in the diagnosis of deep vein thrombosis. Radiology. 1977 Nov;125(2):441–449. doi: 10.1148/125.2.441. [DOI] [PubMed] [Google Scholar]
  4. Fischer J., Wolf R., Leon A. Technetium-99m as a label for erythrocytes. J Nucl Med. 1967 Mar;8(3):229–232. [PubMed] [Google Scholar]
  5. Hirsh J., Gallus A. S. 125-I-labeled fibrinogen scanning. Use in the diagnosis of venous thrombosis. JAMA. 1975 Sep 1;233(9):970–973. doi: 10.1001/jama.233.9.970. [DOI] [PubMed] [Google Scholar]
  6. Hull R., Hirsh J., Sackett D. L., Powers P., Turpie A. G., Walker I. Combined use of leg scanning and impedance plethysmography in suspected venous thrombosis. An alternative to venography. N Engl J Med. 1977 Jun 30;296(26):1497–1500. doi: 10.1056/NEJM197706302962604. [DOI] [PubMed] [Google Scholar]
  7. Millar W. T., Smith J. F. Localisation of deep-venous thrombosis using technetium-99m-labelled urokinase. Lancet. 1974 Sep 21;2(7882):695–696. doi: 10.1016/s0140-6736(74)93267-x. [DOI] [PubMed] [Google Scholar]
  8. Salzman E. W. Diagnosis of deep vein thrombosis. Thromb Diath Haemorrh. 1975 Jun 30;33(3):457–463. [PubMed] [Google Scholar]

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