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. 1975 Nov;16(5):1208–1219. doi: 10.1128/jvi.16.5.1208-1219.1975

Mason-Pfizer monkey virus: analysis and localization of virion proteins and glycoproteins.

G Schochetman, K Kortright, J Schlom
PMCID: PMC355720  PMID: 810603

Abstract

The polypeptide composition of Mason-Pfizer monkey virus was determined using sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Six major polypeptides of molecular weights 68,000, 27,000, 20,000, 14,000, 12,000, and 10,000 were resolved regardless of the cell type (i.e., two human and two rhesus) in which the virus was grown. Protein gp68 (68,000) represented the major virus glycoprotein and protein gp20 (20,000) represented a minor glycoprotein of the virion, again regardless of the cell type of origin of the virus. Protein gp68 appears to be located on the outer surface of the viral envelope, as demonstrated by lactoperoxidase catalyzed iodination of intact virions. Additional glycoproteins were shown to be virion associated; their presence depended, however, on the cell type in which the virus was propagated.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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