Abstract
Echocardiography was used in 30 women and 2 men with systemic lupus erythematosus (SLE) in order to determine the incidence and severity of pericardial effusion and mitral valve involvement. 31 patients showed normal thickness of the mitral valve leaflets, only one patient showed irregular thickening of the leaflets suggesting the presence of vegetations. Mitral valve motions were normal in all patients. These results indicate that myocardial and valvular involvement in SLE is usually not severe enough to result in haemodynamic abnormalities. Pericardial effusion was found in 2 patients who were symptom free, whereas 4 of the patients with a past history suggestive of pericarditis showed no echocardiographic evidence of pericardial effusion. These suggest the transient nature of pericarditis in SLE, and the value of echocardiography as a diagnostic tool in detecting clinically inapparent lupus pericarditis.
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- BRIGDEN W., BYWATERS E. G., LESSOF M. H., ROSS I. P. The heart in systemic lupus erythematosus. Br Heart J. 1960 Jan;22:1–16. doi: 10.1136/hrt.22.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bulkley B. H., Roberts W. C. The heart in systemic lupus erythematosus and the changes induced in it by corticosteroid therapy. A study of 36 necropsy patients. Am J Med. 1975 Feb;58(2):243–264. doi: 10.1016/0002-9343(75)90575-6. [DOI] [PubMed] [Google Scholar]
- Cohen A. S., Canoso J. J. Criteria for the classification of systemic lupus erythematosus--status 1972. Arthritis Rheum. 1972 Sep-Oct;15(5):540–543. doi: 10.1002/art.1780150512. [DOI] [PubMed] [Google Scholar]
- Cosh J. A. The heart and the rheumatic diseases. Rheumatol Phys Med. 1972 May;11(6):267–280. doi: 10.1093/rheumatology/11.6.267. [DOI] [PubMed] [Google Scholar]
- DUBOIS E. L. High dosage steroid therapy for systemic lupus erythematosus. Arthritis Rheum. 1962 Jun;5:250–260. doi: 10.1002/art.1780050305. [DOI] [PubMed] [Google Scholar]
- DeMaria A. N., Miller R. R., Amsterdam E. A., Markson W., Mason D. T. Mitral valve early diastolic closing velocity in the echocardiogram: relation to sequential diastolic flow and ventricular compliance. Am J Cardiol. 1976 Apr;37(5):693–700. doi: 10.1016/0002-9149(76)90362-3. [DOI] [PubMed] [Google Scholar]
- Dillon J. C., Feigenbaum H., Konecke L. L., Davis R. H., Chang S. Echocardiographic manifestations of valvular vegetations. Am Heart J. 1973 Nov;86(5):698–704. doi: 10.1016/0002-8703(73)90350-5. [DOI] [PubMed] [Google Scholar]
- EDLER I. Atrioventricular valve motility in the living human heart recorded by ultrasound. Acta Med Scand Suppl. 1961;370:83–124. doi: 10.1111/j.0954-6820.1961.tb10859.x. [DOI] [PubMed] [Google Scholar]
- Estes D., Christian C. L. The natural history of systemic lupus erythematosus by prospective analysis. Medicine (Baltimore) 1971 Mar;50(2):85–95. doi: 10.1097/00005792-197103000-00001. [DOI] [PubMed] [Google Scholar]
- Feigenbaum H. Echocardiographic diagnosis of pericardial effusion. Am J Cardiol. 1970 Nov;26(5):475–479. doi: 10.1016/0002-9149(70)90705-8. [DOI] [PubMed] [Google Scholar]
- GRIFFITH G. C., VURAL I. L. Acute and subacute disseminated lupus erythematosus; a correlation of clinical and postmortem findings in eighteen cases. Circulation. 1951 Apr;3(4):492–500. doi: 10.1161/01.cir.3.4.492. [DOI] [PubMed] [Google Scholar]
- HARVEY A. M., SHULMAN L. E., TUMULTY P. A., CONLEY C. L., SCHOENRICH E. H. Systemic lupus erythematosus: review of the literature and clinical analysis of 138 cases. Medicine (Baltimore) 1954 Dec;33(4):291–437. [PubMed] [Google Scholar]
- HEJTMANCIK M. R., WRIGHT J. C., QUINT R., JENNINGS F. L. THE CARDIOVASCULAR MANIFESTATIONS OF SYSTEMIC LUPUS ERYTHEMATOSUS. Am Heart J. 1964 Jul;68:119–130. doi: 10.1016/0002-8703(64)90248-0. [DOI] [PubMed] [Google Scholar]
- Horowitz M. S., Schultz C. S., Stinson E. B., Harrison D. C., Popp R. L. Sensitivity and specificity of echocardiographic diagnosis of pericardial effusion. Circulation. 1974 Aug;50(2):239–247. doi: 10.1161/01.cir.50.2.239. [DOI] [PubMed] [Google Scholar]
- Hughes G. R. The diagnosis of systemic lupus erythematosus. Br J Haematol. 1973 Oct;25(4):409–413. doi: 10.1111/j.1365-2141.1973.tb01752.x. [DOI] [PubMed] [Google Scholar]
- JAMES T. N., RUPE C. E., MONTO R. W. PATHOLOGY OF THE CARDIAC CONDUCTION SYSTEM IN SYSTEMIC LUPUS ERYTHEMATOSUS. Ann Intern Med. 1965 Sep;63:402–410. doi: 10.7326/0003-4819-63-3-402. [DOI] [PubMed] [Google Scholar]
- JESSAR R. A., LAMONT-HAVERS R. W., RAGAN C. Natural history of lupus erythematosus disseminatus. Ann Intern Med. 1953 Apr;38(4):717–731. doi: 10.7326/0003-4819-38-4-717. [DOI] [PubMed] [Google Scholar]
- KONG T. Q., KELLUM R. E., HASERICK J. R. Clinical diagnosis of cardiac involvement in systemic lupus erythematosus. A correlation of clinical and autopsy findings in thirty patients. Circulation. 1962 Jul;26:7–11. doi: 10.1161/01.cir.26.1.7. [DOI] [PubMed] [Google Scholar]
- SHEARN M. A. The heart in systemic lupus erythematosus. Am Heart J. 1959 Sep;58:452–466. doi: 10.1016/0002-8703(59)90163-2. [DOI] [PubMed] [Google Scholar]
- Segal B. L., Konecke L. L., Kawai N., Kotler M. N., Linhart J. W. Echocardiography. Current concepts and clinical application. Am J Med. 1974 Aug;57(2):267–283. doi: 10.1016/0002-9343(74)90451-3. [DOI] [PubMed] [Google Scholar]
- TAUBENHAUS M., EISENSTEIN B., PICK A. Cardiovascular manifestations of collagen diseases. Circulation. 1955 Nov;12(5):903–920. doi: 10.1161/01.cir.12.5.903. [DOI] [PubMed] [Google Scholar]
- Zaky A., Nasser W. K., Feigenbaum H. A study of mitral valve action recorded by reflected ultrasound and its application in the diagnosis of mitral stenosis. Circulation. 1968 May;37(5):789–799. doi: 10.1161/01.cir.37.5.789. [DOI] [PubMed] [Google Scholar]