Abstract
The effect of physical training on hemodynamic performance was evaluated in a group of patients who had had a myocardial infarction and a group of healthy, age-matched controls. Before training, the patients' mean ventilatory equivalent was significantly less than that of the controls at the lowest workload (300 kpm/min), the mean stroke volume was significantly increased at the highest workload then achieved (600 kpm/min), and the mean arteriovenous oxygen content difference was significantly smaller at the highest workload. The patients had a relative bradycardia before training and there was no significant reduction in mean resting or submaximal heart rate after training. Their mean oxygen uptake was significantly reduced at the lowest exercise workload after training and this response was significantly different from that of the controls after 8 weeks of training. Mean cardiac output during exercise was significantly reduced in the patients after training, but only at the 600-kpm/min workload, the response being blunted at 900 kpm/min; mean stroke volume was also significantly reduced at this workload after training; both these responses were significantly different from those of the controls Mean arteriovenous oxygen content difference at 6oo kpm/min was significantly increased in the patients after training, though the response was not significantly different from that of the controls. Mean ventilatory equivalent was also significantly increased in patients after training, becoming similar to that of the controls.
Full text
PDF




Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Andrew G. M., Guzman C. A., Becklake M. R. Effect of athletic training on exercise cardiac output. J Appl Physiol. 1966 Mar;21(2):603–608. doi: 10.1152/jappl.1966.21.2.603. [DOI] [PubMed] [Google Scholar]
- BECKLAKE M. R., VARVIS C. J., PENGELLY L. D., KENNING S., McGREGOR M., BATES D. V. Measurement of pulmonary blood flow during exercise using nitrous oxide. J Appl Physiol. 1962 Jul;17:579–586. doi: 10.1152/jappl.1962.17.4.579. [DOI] [PubMed] [Google Scholar]
- CRONIN R. F., MACINTOSH D. J. The relationship of oxygen uptake to muscular exercise in patients with mitral stenosis. Dis Chest. 1962 Nov;42:508–518. doi: 10.1378/chest.42.5.508. [DOI] [PubMed] [Google Scholar]
- Clausen J. P., Larsen O. A., Trap-Jensen J. Physical training in the management of coronary artery disease. Circulation. 1969 Aug;40(2):143–154. doi: 10.1161/01.cir.40.2.143. [DOI] [PubMed] [Google Scholar]
- Clausen J. P., Trap-Jensen J. Effects of training on the distribution of cardiac output in patients with coronary artery disease. Circulation. 1970 Oct;42(4):611–624. doi: 10.1161/01.cir.42.4.611. [DOI] [PubMed] [Google Scholar]
- FOSTER G. L., REEVES T. J. HEMODYNAMIC RESPONSES TO EXERCISE IN CLINICALLY NORMAL MIDDLE-AGED MEN AND IN THOSE WITH ANGINA PECTORIS. J Clin Invest. 1964 Sep;43:1758–1768. doi: 10.1172/JCI105050. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HOLMGREN A., JONSSON B., LEVANDER M., LINDERHOLM H., SJOSTRAND T., STROM G. Low physical working capacity in suspected heart cases due to inadequate adjustment of peripheral blood flow (vasoregulatory asthenia). Acta Med Scand. 1957 Oct 15;158(6):413–436. doi: 10.1111/j.0954-6820.1957.tb15509.x. [DOI] [PubMed] [Google Scholar]
- Hartley L. H., Grimby G., Kilbom A., Nilsson N. J., Astrand I., Bjure J., Ekblom B., Saltin B. Physical training in sedentary middle-aged and older men. 3. Cardiac output and gas exchange asubmaximal and maximal exercise. Scand J Clin Lab Invest. 1969 Dec;24(4):335–344. doi: 10.3109/00365516909080170. [DOI] [PubMed] [Google Scholar]
- Naughton J., McCoy J. F. Observations on the relationship of physical activity to the serum cholesterol concentration of healthy men and cardiac patients. J Chronic Dis. 1966 Jul;19(7):727–733. doi: 10.1016/0021-9681(66)90073-7. [DOI] [PubMed] [Google Scholar]
- Varnauskas E., Bergman H., Houk P., Björntorp P. Haemodynamic effects of physical training in coronary patients. Lancet. 1966 Jul 2;2(7453):8–12. doi: 10.1016/s0140-6736(66)91743-0. [DOI] [PubMed] [Google Scholar]