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. 1979 Jun;38(3):222–225. doi: 10.1136/ard.38.3.222

Airways obstruction in rheumatoid arthritis.

D M Geddes, M Webley, P A Emerson
PMCID: PMC1000439  PMID: 485577

Abstract

Owing to the report of an association between rheumatoid arthritis (RA) and obliterative bronchiolitis we have determined the prevalence of airflow obstruction in unselected patients with RA and normal chest radiographs. Spirometry was performed on 100 patients with rheumatoid arthritis and 84 control subjects matched for age, sex, and smoking habits. Patients with rheumatoid arthritis had significantly lower values for FEV1, FVC, FEV1/FVC, and MMEFR when compared with the controls: 39 patients had abnormal spirometry, and at least 32 showed airways obstruction. The prevalence of airflow obstruction is remarkably high, and we suggest that airway disease may be the commonest form of lung involvement in rheumatoid arthritis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Collins R. L., Turner R. A., Johnson A. M., Whitley N. O., McLean R. L. Obstructive pulmonary disease in rheumatoid arthritis. Arthritis Rheum. 1976 May-Jun;19(3):623–628. doi: 10.1002/art.1780190316. [DOI] [PubMed] [Google Scholar]
  2. Cox D. W., Huber O. Rheumatoid arthritis and alpha-1-antitrypsin. Lancet. 1976 Jun 5;1(7971):1216–1217. doi: 10.1016/s0140-6736(76)92163-2. [DOI] [PubMed] [Google Scholar]
  3. Davidson C., Brooks A. G., Bacon P. A. Lung function in rheumatoid arthritis. A clinic survey. Ann Rheum Dis. 1974 Jul;33(4):293–297. doi: 10.1136/ard.33.4.293. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Frank S. T., Weg J. G., Harkleroad L. E., Fitch R. F. Pulmonary dysfunction in rheumatoid disease. Chest. 1973 Jan;63(1):27–34. doi: 10.1378/chest.63.1.27. [DOI] [PubMed] [Google Scholar]
  5. Geddes D. M., Corrin B., Brewerton D. A., Davies R. J., Turner-Warwick M. Progressive airway obliteration in adults and its association with rheumatoid disease. Q J Med. 1977 Oct;46(184):427–444. [PubMed] [Google Scholar]
  6. Geddes D. M., Webley M., Brewerton D. A., Turton C. W., Turner-Warwick M., Murphy A. H., Ward A. M. alpha 1-antitrypsin phenotypes in fibrosing alveolitis and rheumatoid arthritis. Lancet. 1977 Nov 19;2(8047):1049–1051. doi: 10.1016/s0140-6736(77)91883-9. [DOI] [PubMed] [Google Scholar]
  7. Morris J. F., Koski A., Johnson L. C. Spirometric standards for healthy nonsmoking adults. Am Rev Respir Dis. 1971 Jan;103(1):57–67. doi: 10.1164/arrd.1971.103.1.57. [DOI] [PubMed] [Google Scholar]
  8. Murphy D. M., Fairman R. P., Lapp N. L., Morgan W. K. Severe airway disease due to inhalation of fumes from cleansing agents. Chest. 1976 Mar;69(3):372–376. doi: 10.1378/chest.69.3.372. [DOI] [PubMed] [Google Scholar]
  9. NEWCOMER A. D., MILLER R. D., HEPPER N. G., CARTER E. T. PULMONARY DYSFUNCTION IN RHEUMATOID ARTHRITIS AND SYSTEMIC LUPUS ERYTHEMATOSUS. Dis Chest. 1964 Nov;46:562–570. doi: 10.1378/chest.46.5.562. [DOI] [PubMed] [Google Scholar]
  10. PATTERSON C. D., HARVILLE W. E., PIERCE J. A. RHEUMATOID LUNG DISEASE. Ann Intern Med. 1965 Apr;62:685–697. doi: 10.7326/0003-4819-62-4-685. [DOI] [PubMed] [Google Scholar]
  11. Schernthaner G., Scherak O., Kolarz G., Kummer F. Seropositive rheumatoid arthritis associated with decreased diffusion capacity of the lung. Ann Rheum Dis. 1976 Jun;35(3):258–262. doi: 10.1136/ard.35.3.258. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Walker W. C. Pulmonary infections and rheumatoid arthritis. Q J Med. 1967 Apr;36(142):239–251. [PubMed] [Google Scholar]
  13. Walker W. C., Wright V. Diffuse interstitial pulmonary fibrosis and rheumatoid arthritis. Ann Rheum Dis. 1969 May;28(3):252–259. doi: 10.1136/ard.28.3.252. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Whorwell P. J., Wojtulewski J. A., Lacey B. W. Respiratory function in rheumatoid arthritis. Br Med J. 1975 Apr 26;2(5964):175–175. doi: 10.1136/bmj.2.5964.175. [DOI] [PMC free article] [PubMed] [Google Scholar]

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