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. 1984 Apr;43(2):132–135. doi: 10.1136/ard.43.2.132

Lymphoproliferative malignancy in rheumatoid arthritis: a study of 20 cases.

D P Symmons, M Ahern, P A Bacon, C F Hawkins, P L Amlot, E L Jones, P Prior, D L Scott
PMCID: PMC1001447  PMID: 6712288

Abstract

A series of 20 patients with definite or classical rheumatoid arthritis who subsequently developed a lymphoproliferative malignancy are described. The mean time between the onset of the 2 diseases was 13.2 years. A wide range of types of non-Hodgkin's lymphoma and Hodgkin's disease were found; there were no unusual histological features in the lymphomas. Although many of the patients had had gold, penicillamine, and other second-line drugs, none of them had received cytotoxic drugs, and there was no evidence that therapy was a cause of their malignancies. The likely cause of the association is a predisposition to both diseases.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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