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Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1984 Oct;43(5):746–748. doi: 10.1136/ard.43.5.746

Anticardiolipin antibodies: occurrence in Behçet's syndrome.

R G Hull, E N Harris, A E Gharavi, A Tincani, R A Asherson, G Valesini, A M Denman, G Froude, G R Hughes
PMCID: PMC1001520  PMID: 6497467

Abstract

Anticardiolipin antibodies have recently been described in association with arterial and venous thrombosis, and with neurological symptoms, in connective tissue diseases. In a study of 70 patients with Behçet's syndrome 13 patients had these antibodies. Of these 13 patients eight had a history of either retinal vascular pathology, cerebral infarction, or thrombophlebitis. The association of retinal vascular disease and the presence of anticardiolipin antibodies was statistically significant.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bluestein H. G. Neurocytotoxic antibodies in serum of patients with systemic lupus erythematosus. Proc Natl Acad Sci U S A. 1978 Aug;75(8):3965–3969. doi: 10.1073/pnas.75.8.3965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Bluestein H. G., Zvaifler N. J. Brain-reactive lymphocytotoxic antibodies in the serum of patients with systemic lupus erythematosus. J Clin Invest. 1976 Feb;57(2):509–516. doi: 10.1172/JCI108303. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Boey M. L., Colaco C. B., Gharavi A. E., Elkon K. B., Loizou S., Hughes G. R. Thrombosis in systemic lupus erythematosus: striking association with the presence of circulating lupus anticoagulant. Br Med J (Clin Res Ed) 1983 Oct 8;287(6398):1021–1023. doi: 10.1136/bmj.287.6398.1021. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Bresnihan B., Oliver M., Grigor R., Hughes G. R. Brain reactivity of lymphocytotoxic antibodies in systemic lupus erythematosus with and without cerebral involvement. Clin Exp Immunol. 1977 Dec;30(3):333–337. [PMC free article] [PubMed] [Google Scholar]
  5. Bresnihan B., Oliver M., Williams B., Hughes G. R. An antineuronal antibody cross-reacting with erythrocytes and lymphocytes in systemic lupus erythematosus. Arthritis Rheum. 1979 Apr;22(4):313–320. doi: 10.1002/art.1780220401. [DOI] [PubMed] [Google Scholar]
  6. Harris E. N., Englert H., Derve G., Hughes G. R., Gharavi A. Antiphospholipid antibodies in acute Guillain-Barré syndrome. Lancet. 1983 Dec 10;2(8363):1361–1362. doi: 10.1016/s0140-6736(83)91113-3. [DOI] [PubMed] [Google Scholar]
  7. Harris E. N., Gharavi A. E., Boey M. L., Patel B. M., Mackworth-Young C. G., Loizou S., Hughes G. R. Anticardiolipin antibodies: detection by radioimmunoassay and association with thrombosis in systemic lupus erythematosus. Lancet. 1983 Nov 26;2(8361):1211–1214. doi: 10.1016/s0140-6736(83)91267-9. [DOI] [PubMed] [Google Scholar]
  8. Hirano T., Hashimoto H., Shiokawa Y., Iwamori M., Nagai Y., Kasai M., Ochiai Y., Okumura K. Antiglycolipid autoantibody detected in the sera from systemic lupus erythematosus patients. J Clin Invest. 1980 Dec;66(6):1437–1440. doi: 10.1172/JCI109999. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Landi G., Calloni M. V., Grazia Sabbadini M., Mannuccio Mannucci P., Candelise L. Recurrent ischemic attacks in two young adults with lupus anticoagulant. Stroke. 1983 May-Jun;14(3):377–379. doi: 10.1161/01.str.14.3.377. [DOI] [PubMed] [Google Scholar]
  10. Mason R. M., Barnes C. G. Behçet's syndrome with arthritis. Ann Rheum Dis. 1969 Mar;28(2):95–103. doi: 10.1136/ard.28.2.95. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Mueh J. R., Herbst K. D., Rapaport S. I. Thrombosis in patients with the lupus anticoagulant. Ann Intern Med. 1980 Feb;92(2 Pt 1):156–159. doi: 10.7326/0003-4819-92-2-156. [DOI] [PubMed] [Google Scholar]
  12. O'Duffy J. D., Lehner T., Barnes C. G. Summary of the Third International Conference on Behçet's Disease, Tokyo, Japan, October 23-24, 1981. J Rheumatol. 1983 Feb;10(1):154–158. [PubMed] [Google Scholar]
  13. Shimizu T., Ehrlich G. E., Inaba G., Hayashi K. Behçet disease (Behçet syndrome). Semin Arthritis Rheum. 1979 May;8(4):223–260. doi: 10.1016/0049-0172(79)90004-0. [DOI] [PubMed] [Google Scholar]
  14. Wilson H. A., Winfield J. B., Lahita R. G., Koffler D. Association of IgG anti-brain antibodies with central nervous system dysfunction in systemic lupus erythematosus. Arthritis Rheum. 1979 May;22(5):458–462. doi: 10.1002/art.1780220504. [DOI] [PubMed] [Google Scholar]

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