Abstract
Predominant interstitial nephritis is a rare manifestation of systemic lupus erythematosus. Only seven cases have been reported in the literature. Owing to the rarity of this entity, the natural history of predominant interstitial nephritis in lupus has not been adequately recorded and an appropriate therapeutic approach has yet to be defined. In this report we present the case of a 25 year old woman with active systemic lupus erythematosus complicated by kidney failure and renal tubular acidosis due to predominant interstitial nephritis. We describe the course of her disease over a three year period. Seven additional patients with systemic lupus erythematosus and predominant interstitial nephritis are reviewed.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Cunningham E., Provost T., Brentjens J., Reichlin M., Venuto R. C. Acute renal failure secondary to interstitial lupus nephritis. Arch Intern Med. 1978 Oct;138(10):1560–1561. [PubMed] [Google Scholar]
- Husby G., Tung K. S., Williams R. C., Jr Characterization of renal tissue lymphocytes in patients with interstitial nephritis. Am J Med. 1981 Jan;70(1):31–38. doi: 10.1016/0002-9343(81)90408-3. [DOI] [PubMed] [Google Scholar]
- Makker S. P. Tubular basement membrane antibody-induced interstitial nephritis in systemic lupus erythematosus. Am J Med. 1980 Dec;69(6):949–952. doi: 10.1016/s0002-9343(80)80025-8. [DOI] [PubMed] [Google Scholar]
- Schwartz M. M., Fennell J. S., Lewis E. J. Pathologic changes in the renal tubule in systemic lupus erythematosus. Hum Pathol. 1982 Jun;13(6):534–547. doi: 10.1016/s0046-8177(82)80268-2. [DOI] [PubMed] [Google Scholar]
- Tan E. M., Cohen A. S., Fries J. F., Masi A. T., McShane D. J., Rothfield N. F., Schaller J. G., Talal N., Winchester R. J. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 1982 Nov;25(11):1271–1277. doi: 10.1002/art.1780251101. [DOI] [PubMed] [Google Scholar]
- Tron F., Ganeval D., Droz D. Immunologically-mediated acute renal failure of nonglomerular origin in the course of systemic lupus erythematosus [SLE]. Report of two cases. Am J Med. 1979 Sep;67(3):529–532. doi: 10.1016/0002-9343(79)90806-4. [DOI] [PubMed] [Google Scholar]
- Yeung C. K., Wong K. L., Ng R. P., Ng W. L. Tubular dysfunction in systemic lupus erythematosus. Nephron. 1984;36(2):84–88. doi: 10.1159/000183123. [DOI] [PubMed] [Google Scholar]