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. 1990 May;152(5):573–577.

Pharmacologic approaches to the treatment of cocaine dependence.

W A Taylor 1, M S Gold 1
PMCID: PMC1002413  PMID: 1971975

Abstract

When pharmacologic agents are considered in the treatment of cocaine addiction, the objective of such treatment--sustained abstinence--must be considered. Medication and medical approaches have been disappointing in the treatment of cocaine overdose. The central neurobiologic mechanism(s) involved in cocaine toxicity are poorly understood. Without a cocaine antagonist, pharmacologic approaches have been less than promising in preventing relapse. Various psychoactive medications have been tried in early cocaine abstinence, with some success.

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Selected References

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