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. 1987 Nov;46(11):837–842. doi: 10.1136/ard.46.11.837

Comparison of the immune response to Epstein-Barr virus and cytomegalovirus in sera and synovial fluids of patients with rheumatoid arthritis.

M Musiani 1, M Zerbini 1, S Ferri 1, M Plazzi 1, G Gentilomi 1, M La Placa 1
PMCID: PMC1003402  PMID: 2827590

Abstract

The immune response against two herpesviruses has been determined in sera and matched synovial fluids of patients with rheumatoid arthritis (RA) and compared with that of a healthy control population. The increased level of antibody to Epstein-Barr virus (EBV) induced antigens in patients with RA resembles the antibody pattern observed against cytomegalovirus (CMV) induced antigens, which suggests the presence of a pathological condition in patients with RA that can reactivate latent viral infections. The antibody response against EBV and CMV observed in synovial fluids excludes the local production of specific antibodies against EBV and CMV antigens.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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