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. 1991 Mar;50(3):196–200. doi: 10.1136/ard.50.3.196

A pathological role for damaged hyaluronan in synovitis.

E B Henderson 1, M Grootveld 1, A Farrell 1, E C Smith 1, P W Thompson 1, D R Blake 1
PMCID: PMC1004376  PMID: 2015018

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Selected References

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  1. Ahlgren T., Jarstrand C. Hyaluronic acid enhances phagocytosis of human monocytes in vitro. J Clin Immunol. 1984 May;4(3):246–249. doi: 10.1007/BF00914973. [DOI] [PubMed] [Google Scholar]
  2. Allen R. E., Outhwaite J. M., Morris C. J., Blake D. R. Xanthine oxidoreductase is present in human synovium. Ann Rheum Dis. 1987 Nov;46(11):843–845. doi: 10.1136/ard.46.11.843. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Anastassiades T., Robertson W. Modulation of mitogen-dependent lymphocyte stimulation by hyaluronic acid. J Rheumatol. 1984 Dec;11(6):729–734. [PubMed] [Google Scholar]
  4. Balazs E. A., Laurent T. C., Jeanloz R. W. Nomenclature of hyaluronic acid. Biochem J. 1986 May 1;235(3):903–903. doi: 10.1042/bj2350903. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Balazs E. A., Watson D., Duff I. F., Roseman S. Hyaluronic acid in synovial fluid. I. Molecular parameters of hyaluronic acid in normal and arthritis human fluids. Arthritis Rheum. 1967 Aug;10(4):357–376. doi: 10.1002/art.1780100407. [DOI] [PubMed] [Google Scholar]
  6. Blake D. R., Allen R. E., Lunec J. Free radicals in biological systems--a review orientated to inflammatory processes. Br Med Bull. 1987 Apr;43(2):371–385. doi: 10.1093/oxfordjournals.bmb.a072188. [DOI] [PubMed] [Google Scholar]
  7. Blake D. R., Merry P., Unsworth J., Kidd B. L., Outhwaite J. M., Ballard R., Morris C. J., Gray L., Lunec J. Hypoxic-reperfusion injury in the inflamed human joint. Lancet. 1989 Feb 11;1(8633):289–293. doi: 10.1016/s0140-6736(89)91305-6. [DOI] [PubMed] [Google Scholar]
  8. Bothner H., Wik O. Rheology of hyaluronate. Acta Otolaryngol Suppl. 1987;442:25–30. doi: 10.3109/00016488709102834. [DOI] [PubMed] [Google Scholar]
  9. Dahl L. B., Dahl I. M., Engström-Laurent A., Granath K. Concentration and molecular weight of sodium hyaluronate in synovial fluid from patients with rheumatoid arthritis and other arthropathies. Ann Rheum Dis. 1985 Dec;44(12):817–822. doi: 10.1136/ard.44.12.817. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Dixon A. S., Jacoby R. K., Berry H., Hamilton E. B. Clinical trial of intra-articular injection of sodium hyaluronate in patients with osteoarthritis of the knee. Curr Med Res Opin. 1988;11(4):205–213. doi: 10.1185/03007998809114237. [DOI] [PubMed] [Google Scholar]
  11. Edwards S. W., Hallett M. B., Campbell A. K. Oxygen-radical production during inflammation may be limited by oxygen concentration. Biochem J. 1984 Feb 1;217(3):851–854. doi: 10.1042/bj2170851. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Engström-Laurent A., Hällgren R. Circulating hyaluronate in rheumatoid arthritis: relationship to inflammatory activity and the effect of corticosteroid therapy. Ann Rheum Dis. 1985 Feb;44(2):83–88. doi: 10.1136/ard.44.2.83. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Engström-Laurent A., Hällgren R. Circulating hyaluronic acid levels vary with physical activity in healthy subjects and in rheumatoid arthritis patients. Relationship to synovitis mass and morning stiffness. Arthritis Rheum. 1987 Dec;30(12):1333–1338. doi: 10.1002/art.1780301203. [DOI] [PubMed] [Google Scholar]
  14. Engström-Laurent A., Laurent U. B., Lilja K., Laurent T. C. Concentration of sodium hyaluronate in serum. Scand J Clin Lab Invest. 1985 Oct;45(6):497–504. doi: 10.3109/00365518509155249. [DOI] [PubMed] [Google Scholar]
  15. Falchuk K. H., Goetzl E. J., Kulka J. P. Respiratory gases of synovial fluids. An approach to synovial tissue circulatory-metabolic imbalance in rheumatoid arthritis. Am J Med. 1970 Aug;49(2):223–231. doi: 10.1016/s0002-9343(70)80078-x. [DOI] [PubMed] [Google Scholar]
  16. Forrester J. V., Balazs E. A. Inhibition of phagocytosis by high molecular weight hyaluronate. Immunology. 1980 Jul;40(3):435–446. [PMC free article] [PubMed] [Google Scholar]
  17. Gibbs D. A., Merrill E. W., Smith K. A., Balazs E. A. Rheology of hyaluronic acid. Biopolymers. 1968 Jun;6(6):777–791. doi: 10.1002/bip.1968.360060603. [DOI] [PubMed] [Google Scholar]
  18. Goldberg R. L., Toole B. P. Hyaluronate inhibition of cell proliferation. Arthritis Rheum. 1987 Jul;30(7):769–778. doi: 10.1002/art.1780300707. [DOI] [PubMed] [Google Scholar]
  19. Grootveld M., Henderson E. B., Farrell A., Blake D. R., Parkes H. G., Haycock P. Oxidative damage to hyaluronate and glucose in synovial fluid during exercise of the inflamed rheumatoid joint. Detection of abnormal low-molecular-mass metabolites by proton-n.m.r. spectroscopy. Biochem J. 1991 Jan 15;273(Pt 2):459–467. doi: 10.1042/bj2730459. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Halliwell B. Oxidants and human disease: some new concepts. FASEB J. 1987 Nov;1(5):358–364. [PubMed] [Google Scholar]
  21. Hardingham T. E., Muir H. The specific interaction of hyaluronic acid with cartillage proteoglycans. Biochim Biophys Acta. 1972 Sep 15;279(2):401–405. doi: 10.1016/0304-4165(72)90160-2. [DOI] [PubMed] [Google Scholar]
  22. Hørslev-Petersen K., Bentsen K. D., Engström-Laurent A., Junker P., Halberg P., Lorenzen I. Serum amino terminal type III procollagen peptide and serum hyaluronan in rheumatoid arthritis: relation to clinical and serological parameters of inflammation during 8 and 24 months' treatment with levamisole, penicillamine, or azathioprine. Ann Rheum Dis. 1988 Feb;47(2):116–126. doi: 10.1136/ard.47.2.116. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Jayson M. I., St Dixon A. J. Intra-articular pressure in rheumatoid arthritis of the knee. I. Pressure changes during passive joint distension. Ann Rheum Dis. 1970 May;29(3):261–265. doi: 10.1136/ard.29.3.261. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Lacy B. E., Underhill C. B. The hyaluronate receptor is associated with actin filaments. J Cell Biol. 1987 Sep;105(3):1395–1404. doi: 10.1083/jcb.105.3.1395. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Laurent T. C. Biochemistry of hyaluronan. Acta Otolaryngol Suppl. 1987;442:7–24. doi: 10.3109/00016488709102833. [DOI] [PubMed] [Google Scholar]
  26. Lund-Olesen K. Oxygen tension in synovial fluids. Arthritis Rheum. 1970 Nov-Dec;13(6):769–776. doi: 10.1002/art.1780130606. [DOI] [PubMed] [Google Scholar]
  27. Lunec J., Blake D. R., McCleary S. J., Brailsford S., Bacon P. A. Self-perpetuating mechanisms of immunoglobulin G aggregation in rheumatoid inflammation. J Clin Invest. 1985 Dec;76(6):2084–2090. doi: 10.1172/JCI112212. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Lunec J., Blake D. R. The determination of dehydroascorbic acid and ascorbic acid in the serum and synovial fluid of patients with rheumatoid arthritis (RA). Free Radic Res Commun. 1985;1(1):31–39. doi: 10.3109/10715768509056534. [DOI] [PubMed] [Google Scholar]
  29. Martin-Amat G., McMartin K. E., Hayreh S. S., Hayreh M. S., Tephly T. R. Methanol poisoning: ocular toxicity produced by formate. Toxicol Appl Pharmacol. 1978 Jul;45(1):201–208. doi: 10.1016/0041-008x(78)90040-6. [DOI] [PubMed] [Google Scholar]
  30. McCord J. M. Oxygen-derived free radicals in postischemic tissue injury. N Engl J Med. 1985 Jan 17;312(3):159–163. doi: 10.1056/NEJM198501173120305. [DOI] [PubMed] [Google Scholar]
  31. McMartin K. E., Ambre J. J., Tephly T. R. Methanol poisoning in human subjects. Role for formic acid accumulation in the metabolic acidosis. Am J Med. 1980 Mar;68(3):414–418. doi: 10.1016/0002-9343(80)90113-8. [DOI] [PubMed] [Google Scholar]
  32. McNeil J. D., Wiebkin O. W., Betts W. H., Cleland L. G. Depolymerisation products of hyaluronic acid after exposure to oxygen-derived free radicals. Ann Rheum Dis. 1985 Nov;44(11):780–789. doi: 10.1136/ard.44.11.780. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. Merry P., Winyard P. G., Morris C. J., Grootveld M., Blake D. R. Oxygen free radicals, inflammation, and synovitis: and synovitis: the current status. Ann Rheum Dis. 1989 Oct;48(10):864–870. doi: 10.1136/ard.48.10.864. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. Morris C. J., Blake D. R., Wainwright A. C., Steven M. M. Relationship between iron deposits and tissue damage in the synovium: an ultrastructural study. Ann Rheum Dis. 1986 Jan;45(1):21–26. doi: 10.1136/ard.45.1.21. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. Namiki O., Toyoshima H., Morisaki N. Therapeutic effect of intra-articular injection of high molecular weight hyaluronic acid on osteoarthritis of the knee. Int J Clin Pharmacol Ther Toxicol. 1982 Nov;20(11):501–507. [PubMed] [Google Scholar]
  36. Ng C. K., Handley C. J., Mason R. M., Robinson H. C. Synthesis of hyaluronate in cultured bovine articular cartilage. Biochem J. 1989 Nov 1;263(3):761–767. doi: 10.1042/bj2630761. [DOI] [PMC free article] [PubMed] [Google Scholar]
  37. Peyron J. G., Balazs E. A. Preliminary clinical assessment of Na-hyaluronate injection into human arthritic joints. Pathol Biol (Paris) 1974 Oct;22(8):731–736. [PubMed] [Google Scholar]
  38. Prehm P. Release of hyaluronate from eukaryotic cells. Biochem J. 1990 Apr 1;267(1):185–189. doi: 10.1042/bj2670185. [DOI] [PMC free article] [PubMed] [Google Scholar]
  39. Punzi L., Schiavon F., Cavasin F., Ramonda R., Gambari P. F., Todesco S. The influence of intra-articular hyaluronic acid on PGE2 and cAMP of synovial fluid. Clin Exp Rheumatol. 1989 May-Jun;7(3):247–250. [PubMed] [Google Scholar]
  40. Rowley D., Gutteridge J. M., Blake D., Farr M., Halliwell B. Lipid peroxidation in rheumatoid arthritis: thiobarbituric acid-reactive material and catalytic iron salts in synovial fluid from rheumatoid patients. Clin Sci (Lond) 1984 Jun;66(6):691–695. doi: 10.1042/cs0660691. [DOI] [PubMed] [Google Scholar]
  41. Shichikawa K., Maeda A., Ogawa N. [Clinical evaluation of sodium hyaluronate in the treatment of osteoarthritis of the knee]. Ryumachi. 1983 Aug;23(4):280–290. [PubMed] [Google Scholar]
  42. Underhill C. B., Chi-Rosso G., Toole B. P. Effects of detergent solubilization on the hyaluronate-binding protein from membranes of simian virus 40-transformed 3T3 cells. J Biol Chem. 1983 Jul 10;258(13):8086–8091. [PubMed] [Google Scholar]
  43. Underhill C. B., Green S. J., Comoglio P. M., Tarone G. The hyaluronate receptor is identical to a glycoprotein of Mr 85,000 (gp85) as shown by a monoclonal antibody that interferes with binding activity. J Biol Chem. 1987 Sep 25;262(27):13142–13146. [PubMed] [Google Scholar]
  44. Underhill C. B., Thurn A. L., Lacy B. E. Characterization and identification of the hyaluronate binding site from membranes of SV-3T3 cells. J Biol Chem. 1985 Jul 5;260(13):8128–8133. [PubMed] [Google Scholar]
  45. West D. C., Hampson I. N., Arnold F., Kumar S. Angiogenesis induced by degradation products of hyaluronic acid. Science. 1985 Jun 14;228(4705):1324–1326. doi: 10.1126/science.2408340. [DOI] [PubMed] [Google Scholar]
  46. Wong P. S., Travis J. Isolation and properties of oxidized alpha-1-proteinase inhibitor from human rheumatoid synovial fluid. Biochem Biophys Res Commun. 1980 Oct 16;96(3):1449–1454. doi: 10.1016/0006-291x(80)90113-8. [DOI] [PubMed] [Google Scholar]
  47. Woodruff T., Blake D. R., Freeman J., Andrews F. J., Salt P., Lunec J. Is chronic synovitis an example of reperfusion injury? Ann Rheum Dis. 1986 Jul;45(7):608–611. doi: 10.1136/ard.45.7.608. [DOI] [PMC free article] [PubMed] [Google Scholar]

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