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. 1993 May;52(5):387–412. doi: 10.1136/ard.52.5.387

2nd European Symposium on Lyme Borreliosis. A NATO advanced research workshop. United Kingdom, 19-20 May 1993. Abstracts.

PMCID: PMC1005059  PMID: 8100701

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Selected References

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  1. Asbrink E. Erythema chronicum migrans Afzelius and acrodermatitis chronica atrophicans. Early and late manifestations of Ixodes ricinus-borne Borrelia spirochetes. Acta Derm Venereol Suppl (Stockh) 1985;118:1–63. [PubMed] [Google Scholar]
  2. Asbrink E., Hovmark A. Early and late cutaneous manifestations in Ixodes-borne borreliosis (erythema migrans borreliosis, Lyme borreliosis). Ann N Y Acad Sci. 1988;539:4–15. doi: 10.1111/j.1749-6632.1988.tb31833.x. [DOI] [PubMed] [Google Scholar]
  3. Asbrink E., Olsson I., Hovmark A. Erythema chronicum migrans Afzelius in Sweden. A study on 231 patients. Zentralbl Bakteriol Mikrobiol Hyg A. 1986 Dec;263(1-2):229–236. doi: 10.1016/s0176-6724(86)80126-2. [DOI] [PubMed] [Google Scholar]
  4. Axford J. S., Watts R. A., Long A. A., Isenberg D. A., Steere A. C. Expression of public idiotypes in patients with Lyme arthritis. Ann Rheum Dis. 1993 Mar;52(3):199–205. doi: 10.1136/ard.52.3.199. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Baig S., Olsson T., Link H. Predominance of Borrelia burgdorferi specific B cells in cerebrospinal fluid in neuroborreliosis. Lancet. 1989 Jul 8;2(8654):71–74. doi: 10.1016/s0140-6736(89)90314-0. [DOI] [PubMed] [Google Scholar]
  6. Baranton G., Postic D., Saint Girons I., Boerlin P., Piffaretti J. C., Assous M., Grimont P. A. Delineation of Borrelia burgdorferi sensu stricto, Borrelia garinii sp. nov., and group VS461 associated with Lyme borreliosis. Int J Syst Bacteriol. 1992 Jul;42(3):378–383. doi: 10.1099/00207713-42-3-378. [DOI] [PubMed] [Google Scholar]
  7. Baranton G., Postic D., Saint Girons I., Boerlin P., Piffaretti J. C., Assous M., Grimont P. A. Delineation of Borrelia burgdorferi sensu stricto, Borrelia garinii sp. nov., and group VS461 associated with Lyme borreliosis. Int J Syst Bacteriol. 1992 Jul;42(3):378–383. doi: 10.1099/00207713-42-3-378. [DOI] [PubMed] [Google Scholar]
  8. Baranton G., Postic D., Saint Girons I., Boerlin P., Piffaretti J. C., Assous M., Grimont P. A. Delineation of Borrelia burgdorferi sensu stricto, Borrelia garinii sp. nov., and group VS461 associated with Lyme borreliosis. Int J Syst Bacteriol. 1992 Jul;42(3):378–383. doi: 10.1099/00207713-42-3-378. [DOI] [PubMed] [Google Scholar]
  9. Baranton G., Postic D., Saint Girons I., Boerlin P., Piffaretti J. C., Assous M., Grimont P. A. Delineation of Borrelia burgdorferi sensu stricto, Borrelia garinii sp. nov., and group VS461 associated with Lyme borreliosis. Int J Syst Bacteriol. 1992 Jul;42(3):378–383. doi: 10.1099/00207713-42-3-378. [DOI] [PubMed] [Google Scholar]
  10. Baranton G., Postic D., Saint Girons I., Boerlin P., Piffaretti J. C., Assous M., Grimont P. A. Delineation of Borrelia burgdorferi sensu stricto, Borrelia garinii sp. nov., and group VS461 associated with Lyme borreliosis. Int J Syst Bacteriol. 1992 Jul;42(3):378–383. doi: 10.1099/00207713-42-3-378. [DOI] [PubMed] [Google Scholar]
  11. Barbour A. G., Heiland R. A., Howe T. R. Heterogeneity of major proteins in Lyme disease borreliae: a molecular analysis of North American and European isolates. J Infect Dis. 1985 Sep;152(3):478–484. doi: 10.1093/infdis/152.3.478. [DOI] [PubMed] [Google Scholar]
  12. Berardi V. P., Weeks K. E., Steere A. C. Serodiagnosis of early Lyme disease: analysis of IgM and IgG antibody responses by using an antibody-capture enzyme immunoassay. J Infect Dis. 1988 Oct;158(4):754–760. doi: 10.1093/infdis/158.4.754. [DOI] [PubMed] [Google Scholar]
  13. Berger B. W., MacDonald A. B., Benach J. L. Use of an autologous antigen in the serologic testing of patients with erythema migrans of Lyme disease. J Am Acad Dermatol. 1988 Jun;18(6):1243–1246. doi: 10.1016/s0190-9622(88)70129-2. [DOI] [PubMed] [Google Scholar]
  14. Bianchi G., Rovetta G., Monteforte P., Fumarola D., Trevisan G., Crovato F., Cimmino M. A. Articular involvement in European patients with Lyme disease. A report of 32 Italian patients. Br J Rheumatol. 1990 Jun;29(3):178–180. doi: 10.1093/rheumatology/29.3.178. [DOI] [PubMed] [Google Scholar]
  15. Burgdorfer W., Barbour A. G., Hayes S. F., Benach J. L., Grunwaldt E., Davis J. P. Lyme disease-a tick-borne spirochetosis? Science. 1982 Jun 18;216(4552):1317–1319. doi: 10.1126/science.7043737. [DOI] [PubMed] [Google Scholar]
  16. Carreiro M. M., Laux D. C., Nelson D. R. Characterization of the heat shock response and identification of heat shock protein antigens of Borrelia burgdorferi. Infect Immun. 1990 Jul;58(7):2186–2191. doi: 10.1128/iai.58.7.2186-2191.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Carreiro M. M., Laux D. C., Nelson D. R. Characterization of the heat shock response and identification of heat shock protein antigens of Borrelia burgdorferi. Infect Immun. 1990 Jul;58(7):2186–2191. doi: 10.1128/iai.58.7.2186-2191.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Cutler S. J., Wright D. J. Comparison of immunofluorescence and enzyme linked immunosorbent assays for diagnosing Lyme disease. J Clin Pathol. 1989 Aug;42(8):869–871. doi: 10.1136/jcp.42.8.869. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Dattwyler R. J., Halperin J. J., Volkman D. J., Luft B. J. Treatment of late Lyme borreliosis--randomised comparison of ceftriaxone and penicillin. Lancet. 1988 May 28;1(8596):1191–1194. doi: 10.1016/s0140-6736(88)92011-9. [DOI] [PubMed] [Google Scholar]
  20. Dattwyler R. J., Volkman D. J., Conaty S. M., Platkin S. P., Luft B. J. Amoxycillin plus probenecid versus doxycycline for treatment of erythema migrans borreliosis. Lancet. 1990 Dec 8;336(8728):1404–1406. doi: 10.1016/0140-6736(90)93103-v. [DOI] [PubMed] [Google Scholar]
  21. Dattwyler R. J., Volkman D. J., Luft B. J., Halperin J. J., Thomas J., Golightly M. G. Seronegative Lyme disease. Dissociation of specific T- and B-lymphocyte responses to Borrelia burgdorferi. N Engl J Med. 1988 Dec 1;319(22):1441–1446. doi: 10.1056/NEJM198812013192203. [DOI] [PubMed] [Google Scholar]
  22. Davidson B. E., MacDougall J., Saint Girons I. Physical map of the linear chromosome of the bacterium Borrelia burgdorferi 212, a causative agent of Lyme disease, and localization of rRNA genes. J Bacteriol. 1992 Jun;174(11):3766–3774. doi: 10.1128/jb.174.11.3766-3774.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Debue M., Gautier P., Hackel C., Van Elsen A., Herzog A., Bigaignon G., Bollen A. Detection of Borrelia burgdorferi in biological samples using the polymerase chain reaction assay. Res Microbiol. 1991 Jun;142(5):565–572. doi: 10.1016/0923-2508(91)90189-h. [DOI] [PubMed] [Google Scholar]
  24. Dinerman H., Steere A. C. Lyme disease associated with fibromyalgia. Ann Intern Med. 1992 Aug 15;117(4):281–285. doi: 10.7326/0003-4819-117-4-281. [DOI] [PubMed] [Google Scholar]
  25. Dressler F., Whalen J. A., Reinhardt B. N., Steere A. C. Western blotting in the serodiagnosis of Lyme disease. J Infect Dis. 1993 Feb;167(2):392–400. doi: 10.1093/infdis/167.2.392. [DOI] [PubMed] [Google Scholar]
  26. Dunica S., Piette J. C., Nassar N., Beaufils P. Une nouvelle cause de bloc auriculo-ventriculaire aigu transitoire: la maladie de Lyme. Arch Mal Coeur Vaiss. 1986 Jul;79(8):1251–1255. [PubMed] [Google Scholar]
  27. Eiffert H., Lotter H., Thomssen R. Use of peroxidase-labelled antigen for the detection of antibodies to Borrelia burgdorferi in human and animal sera. Scand J Infect Dis. 1991;23(1):79–87. doi: 10.3109/00365549109023378. [DOI] [PubMed] [Google Scholar]
  28. Fahrer H., van der Linden S. M., Sauvain M. J., Gern L., Zhioua E., Aeschlimann A. The prevalence and incidence of clinical and asymptomatic Lyme borreliosis in a population at risk. J Infect Dis. 1991 Feb;163(2):305–310. doi: 10.1093/infdis/163.2.305. [DOI] [PubMed] [Google Scholar]
  29. Fikrig E., Barthold S. W., Kantor F. S., Flavell R. A. Protection of mice against the Lyme disease agent by immunizing with recombinant OspA. Science. 1990 Oct 26;250(4980):553–556. doi: 10.1126/science.2237407. [DOI] [PubMed] [Google Scholar]
  30. Fikrig E., Telford S. R., 3rd, Barthold S. W., Kantor F. S., Spielman A., Flavell R. A. Elimination of Borrelia burgdorferi from vector ticks feeding on OspA-immunized mice. Proc Natl Acad Sci U S A. 1992 Jun 15;89(12):5418–5421. doi: 10.1073/pnas.89.12.5418. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. Georgilis K., Peacocke M., Klempner M. S. Fibroblasts protect the Lyme disease spirochete, Borrelia burgdorferi, from ceftriaxone in vitro. J Infect Dis. 1992 Aug;166(2):440–444. doi: 10.1093/infdis/166.2.440. [DOI] [PubMed] [Google Scholar]
  32. Gern L., Toutoungi L. N., Hu C. M., Aeschlimann A. Ixodes (Pholeoixodes) hexagonus, an efficient vector of Borrelia burgdorferi in the laboratory. Med Vet Entomol. 1991 Oct;5(4):431–435. doi: 10.1111/j.1365-2915.1991.tb00571.x. [DOI] [PubMed] [Google Scholar]
  33. Goodman J. L., Jurkovich P., Kramber J. M., Johnson R. C. Molecular detection of persistent Borrelia burgdorferi in the urine of patients with active Lyme disease. Infect Immun. 1991 Jan;59(1):269–278. doi: 10.1128/iai.59.1.269-278.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. Grodzicki R. L., Steere A. C. Comparison of immunoblotting and indirect enzyme-linked immunosorbent assay using different antigen preparations for diagnosing early Lyme disease. J Infect Dis. 1988 Apr;157(4):790–797. doi: 10.1093/infdis/157.4.790. [DOI] [PubMed] [Google Scholar]
  35. Grodzicki R. L., Steere A. C. Comparison of immunoblotting and indirect enzyme-linked immunosorbent assay using different antigen preparations for diagnosing early Lyme disease. J Infect Dis. 1988 Apr;157(4):790–797. doi: 10.1093/infdis/157.4.790. [DOI] [PubMed] [Google Scholar]
  36. Gustafson R., Svenungsson B., Gardulf A., Stiernstedt G., Forsgren M. Prevalence of tick-borne encephalitis and Lyme borreliosis in a defined Swedish population. Scand J Infect Dis. 1990;22(3):297–306. doi: 10.3109/00365549009027051. [DOI] [PubMed] [Google Scholar]
  37. Guy E. C., Farquhar R. G. Borrelia burgdorferi in urban parks. Lancet. 1991 Jul 27;338(8761):253–253. doi: 10.1016/0140-6736(91)90392-3. [DOI] [PubMed] [Google Scholar]
  38. Guy E. C., Stanek G. Detection of Borrelia burgdorferi in patients with Lyme disease by the polymerase chain reaction. J Clin Pathol. 1991 Jul;44(7):610–611. doi: 10.1136/jcp.44.7.610. [DOI] [PMC free article] [PubMed] [Google Scholar]
  39. Guy E. C., Stanek G. Detection of Borrelia burgdorferi in patients with Lyme disease by the polymerase chain reaction. J Clin Pathol. 1991 Jul;44(7):610–611. doi: 10.1136/jcp.44.7.610. [DOI] [PMC free article] [PubMed] [Google Scholar]
  40. Halperin J. J. North American Lyme neuroborreliosis. Scand J Infect Dis Suppl. 1991;77:74–80. [PubMed] [Google Scholar]
  41. Halperin J. J. North American Lyme neuroborreliosis. Scand J Infect Dis Suppl. 1991;77:74–80. [PubMed] [Google Scholar]
  42. Hansen K., Bangsborg J. M., Fjordvang H., Pedersen N. S., Hindersson P. Immunochemical characterization of and isolation of the gene for a Borrelia burgdorferi immunodominant 60-kilodalton antigen common to a wide range of bacteria. Infect Immun. 1988 Aug;56(8):2047–2053. doi: 10.1128/iai.56.8.2047-2053.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
  43. Hansen K., Hindersson P., Pedersen N. S. Measurement of antibodies to the Borrelia burgdorferi flagellum improves serodiagnosis in Lyme disease. J Clin Microbiol. 1988 Feb;26(2):338–346. doi: 10.1128/jcm.26.2.338-346.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
  44. Hansen K., Hovmark A., Lebech A. M., Lebech K., Olsson I., Halkier-Sørensen L., Olsson E., Asbrink E. Roxithromycin in Lyme borreliosis: discrepant results of an in vitro and in vivo animal susceptibility study and a clinical trial in patients with erythema migrans. Acta Derm Venereol. 1992 Aug;72(4):297–300. [PubMed] [Google Scholar]
  45. Hansen K., Lebech A. M. Lyme neuroborreliosis: a new sensitive diagnostic assay for intrathecal synthesis of Borrelia burgdorferi--specific immunoglobulin G, A, and M. Ann Neurol. 1991 Aug;30(2):197–205. doi: 10.1002/ana.410300212. [DOI] [PubMed] [Google Scholar]
  46. Hansen K., Lebech A. M. The clinical and epidemiological profile of Lyme neuroborreliosis in Denmark 1985-1990. A prospective study of 187 patients with Borrelia burgdorferi specific intrathecal antibody production. Brain. 1992 Apr;115(Pt 2):399–423. doi: 10.1093/brain/115.2.399. [DOI] [PubMed] [Google Scholar]
  47. Hardin J. A., Steere A. C., Malawista S. E. Immune complexes and the evolution of Lyme arthritis. Dissemination and localization of abnormal C1q binding activity. N Engl J Med. 1979 Dec 20;301(25):1358–1363. doi: 10.1056/NEJM197912203012502. [DOI] [PubMed] [Google Scholar]
  48. Hassler D., Zöller L., Haude M., Hufnagel H. D., Heinrich F., Sonntag H. G. Cefotaxime versus penicillin in the late stage of Lyme disease--prospective, randomized therapeutic study. Infection. 1990 Jan-Feb;18(1):16–20. doi: 10.1007/BF01644175. [DOI] [PubMed] [Google Scholar]
  49. Hederstedt B., Hovmark A., Stiernstedt G., Asbrink E. Borrelia-diagnos aktuell året om visar serologisk undersökning av 1985 års fall. Lakartidningen. 1986 Nov 19;83(47):3987–3989. [PubMed] [Google Scholar]
  50. Herzer P. Joint manifestations of Lyme borreliosis in Europe. Scand J Infect Dis Suppl. 1991;77:55–63. [PubMed] [Google Scholar]
  51. Huppertz H. I. Childhood Lyme borreliosis in Europe. Eur J Pediatr. 1990 Sep;149(12):814–821. doi: 10.1007/BF02072065. [DOI] [PubMed] [Google Scholar]
  52. Jaenson T. G., Tälleklint L. Incompetence of roe deer as reservoirs of the Lyme borreliosis spirochete. J Med Entomol. 1992 Sep;29(5):813–817. doi: 10.1093/jmedent/29.5.813. [DOI] [PubMed] [Google Scholar]
  53. Jörbeck H. J., Gustafsson P. M., Lind H. C., Stiernstedt G. T. Tick-borne Borrelia-meningitis in children. An outbreak in the Kalmar area during the summer of 1984. Acta Paediatr Scand. 1987 Mar;76(2):228–233. doi: 10.1111/j.1651-2227.1987.tb10452.x. [DOI] [PubMed] [Google Scholar]
  54. Karlsson M. Antibody response against autologous and heterologous isolates of Borrelia burgdorferi in four patients with Lyme neuroborreliosis. Eur J Clin Microbiol Infect Dis. 1991 Sep;10(9):742–745. doi: 10.1007/BF01972499. [DOI] [PubMed] [Google Scholar]
  55. Keller T. L., Halperin J. J., Whitman M. PCR detection of Borrelia burgdorferi DNA in cerebrospinal fluid of Lyme neuroborreliosis patients. Neurology. 1992 Jan;42(1):32–42. doi: 10.1212/wnl.42.1.32. [DOI] [PubMed] [Google Scholar]
  56. Kohler J., Kern U., Kasper J., Rhese-Küpper B., Thoden U. Chronic central nervous system involvement in Lyme borreliosis. Neurology. 1988 Jun;38(6):863–867. doi: 10.1212/wnl.38.6.863. [DOI] [PubMed] [Google Scholar]
  57. Kohlhepp W., Oschmann P., Mertens H. G. Treatment of Lyme borreliosis. Randomized comparison of doxycycline and penicillin G. J Neurol. 1989 Dec;236(8):464–469. doi: 10.1007/BF00328508. [DOI] [PubMed] [Google Scholar]
  58. Krause A., Burmester G. R., Rensing A., Schoerner C., Schaible U. E., Simon M. M., Herzer P., Kramer M. D., Wallich R. Cellular immune reactivity to recombinant OspA and flagellin from Borrelia burgdorferi in patients with Lyme borreliosis. Complexity of humoral and cellular immune responses. J Clin Invest. 1992 Sep;90(3):1077–1084. doi: 10.1172/JCI115923. [DOI] [PMC free article] [PubMed] [Google Scholar]
  59. Kristoferitsch W. Neurological manifestations of Lyme borreliosis: clinical definition and differential diagnosis. Scand J Infect Dis Suppl. 1991;77:64–73. [PubMed] [Google Scholar]
  60. Kristoferitsch W., Sluga E., Graf M., Partsch H., Neumann R., Stanek G., Budka H. Neuropathy associated with acrodermatitis chronica atrophicans. Clinical and morphological features. Ann N Y Acad Sci. 1988;539:35–45. doi: 10.1111/j.1749-6632.1988.tb31836.x. [DOI] [PubMed] [Google Scholar]
  61. Kujala G. A., Steere A. C., Davis J. S., 4th IgM rheumatoid factor in Lyme disease: correlation with disease activity, total serum IgM, and IgM antibody to Borrelia burgdorferi. J Rheumatol. 1987 Aug;14(4):772–776. [PubMed] [Google Scholar]
  62. Lebech A. M., Hansen K. Detection of Borrelia burgdorferi DNA in urine samples and cerebrospinal fluid samples from patients with early and late Lyme neuroborreliosis by polymerase chain reaction. J Clin Microbiol. 1992 Jul;30(7):1646–1653. doi: 10.1128/jcm.30.7.1646-1653.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  63. Lebech A. M., Hindersson P., Vuust J., Hansen K. Comparison of in vitro culture and polymerase chain reaction for detection of Borrelia burgdorferi in tissue from experimentally infected animals. J Clin Microbiol. 1991 Apr;29(4):731–737. doi: 10.1128/jcm.29.4.731-737.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
  64. Luft B. J., Steinman C. R., Neimark H. C., Muralidhar B., Rush T., Finkel M. F., Kunkel M., Dattwyler R. J. Invasion of the central nervous system by Borrelia burgdorferi in acute disseminated infection. JAMA. 1992 Mar 11;267(10):1364–1367. [PubMed] [Google Scholar]
  65. Luger S. W. Lyme disease transmitted by a biting fly. N Engl J Med. 1990 Jun 14;322(24):1752–1752. doi: 10.1056/NEJM199006143222415. [DOI] [PubMed] [Google Scholar]
  66. Ma B., Christen B., Leung D., Vigo-Pelfrey C. Serodiagnosis of Lyme borreliosis by western immunoblot: reactivity of various significant antibodies against Borrelia burgdorferi. J Clin Microbiol. 1992 Feb;30(2):370–376. doi: 10.1128/jcm.30.2.370-376.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  67. Mackworth-Young C. G., Harris E. N., Steere A. C., Rizvi F., Malawista S. E., Hughes G. R., Gharavi A. E. Anticardiolipin antibodies in Lyme disease. Arthritis Rheum. 1988 Aug;31(8):1052–1056. doi: 10.1002/art.1780310818. [DOI] [PubMed] [Google Scholar]
  68. Magnarelli L. A., Anderson J. F., Barbour A. G. Enzyme-linked immunosorbent assays for Lyme disease: reactivity of subunits of Borrelia burgdorferi. J Infect Dis. 1989 Jan;159(1):43–49. doi: 10.1093/infdis/159.1.43. [DOI] [PubMed] [Google Scholar]
  69. Magnarelli L. A., Fikrig E., Berland R., Anderson J. F., Flavell R. A. Comparison of whole-cell antibodies and an antigenic flagellar epitope of Borrelia burgdorferi in serologic tests for diagnosis of Lyme borreliosis. J Clin Microbiol. 1992 Dec;30(12):3158–3162. doi: 10.1128/jcm.30.12.3158-3162.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  70. Magnarelli L. A., Miller J. N., Anderson J. F., Riviere G. R. Cross-reactivity of nonspecific treponemal antibody in serologic tests for Lyme disease. J Clin Microbiol. 1990 Jun;28(6):1276–1279. doi: 10.1128/jcm.28.6.1276-1279.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
  71. Matteson E. L., Beckett V. L., O'Fallon W. M., Melton L. J., 3rd, Duffy J. Epidemiology of Lyme disease in Olmsted County, MN, 1975-1990. J Rheumatol. 1992 Nov;19(11):1743–1745. [PubMed] [Google Scholar]
  72. Melchers W., Meis J., Rosa P., Claas E., Nohlmans L., Koopman R., Horrevorts A., Galama J. Amplification of Borrelia burgdorferi DNA in skin biopsies from patients with Lyme disease. J Clin Microbiol. 1991 Nov;29(11):2401–2406. doi: 10.1128/jcm.29.11.2401-2406.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
  73. Miller L. C., Isa S., Vannier E., Georgilis K., Steere A. C., Dinarello C. A. Live Borrelia burgdorferi preferentially activate interleukin-1 beta gene expression and protein synthesis over the interleukin-1 receptor antagonist. J Clin Invest. 1992 Sep;90(3):906–912. doi: 10.1172/JCI115966. [DOI] [PMC free article] [PubMed] [Google Scholar]
  74. Miller L. C., Lynch E. A., Isa S., Logan J. W., Dinarello C. A., Steere A. C. Balance of synovial fluid IL-1 beta and IL-1 receptor antagonist and recovery from Lyme arthritis. Lancet. 1993 Jan 16;341(8838):146–148. doi: 10.1016/0140-6736(93)90006-3. [DOI] [PubMed] [Google Scholar]
  75. Old I. G., MacDougall J., Saint Girons I., Davidson B. E. Mapping of genes on the linear chromosome of the bacterium Borrelia burgdorferi: possible locations for its origin of replication. FEMS Microbiol Lett. 1992 Dec 1;78(2-3):245–250. doi: 10.1016/0378-1097(92)90034-l. [DOI] [PubMed] [Google Scholar]
  76. Panaccio M., Lew A. PCR based diagnosis in the presence of 8% (v/v) blood. Nucleic Acids Res. 1991 Mar 11;19(5):1151–1151. doi: 10.1093/nar/19.5.1151. [DOI] [PMC free article] [PubMed] [Google Scholar]
  77. Persing D. H., Telford S. R., 3rd, Spielman A., Barthold S. W. Detection of Borrelia burgdorferi infection in Ixodes dammini ticks with the polymerase chain reaction. J Clin Microbiol. 1990 Mar;28(3):566–572. doi: 10.1128/jcm.28.3.566-572.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
  78. Pfister H. W., Preac-Mursic V., Wilske B., Einhäupl K. M. Cefotaxime vs penicillin G for acute neurologic manifestations in Lyme borreliosis. A prospective randomized study. Arch Neurol. 1989 Nov;46(11):1190–1194. doi: 10.1001/archneur.1989.00520470044025. [DOI] [PubMed] [Google Scholar]
  79. Preac-Mursic V., Weber K., Pfister H. W., Wilske B., Gross B., Baumann A., Prokop J. Survival of Borrelia burgdorferi in antibiotically treated patients with Lyme borreliosis. Infection. 1989 Nov-Dec;17(6):355–359. doi: 10.1007/BF01645543. [DOI] [PubMed] [Google Scholar]
  80. Rittig M. G., Krause A., Häupl T., Schaible U. E., Modolell M., Kramer M. D., Lütjen-Drecoll E., Simon M. M., Burmester G. R. Coiling phagocytosis is the preferential phagocytic mechanism for Borrelia burgdorferi. Infect Immun. 1992 Oct;60(10):4205–4212. doi: 10.1128/iai.60.10.4205-4212.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  81. Rosa P. A., Schwan T. G. A specific and sensitive assay for the Lyme disease spirochete Borrelia burgdorferi using the polymerase chain reaction. J Infect Dis. 1989 Dec;160(6):1018–1029. doi: 10.1093/infdis/160.6.1018. [DOI] [PubMed] [Google Scholar]
  82. Rubin D. A., Sorbera C., Nikitin P., McAllister A., Wormser G. P., Nadelman R. B. Prospective evaluation of heart block complicating early Lyme disease. Pacing Clin Electrophysiol. 1992 Mar;15(3):252–255. doi: 10.1111/j.1540-8159.1992.tb06492.x. [DOI] [PubMed] [Google Scholar]
  83. Schaible U. E., Kramer M. D., Wallich R., Tran T., Simon M. M. Experimental Borrelia burgdorferi infection in inbred mouse strains: antibody response and association of H-2 genes with resistance and susceptibility to development of arthritis. Eur J Immunol. 1991 Oct;21(10):2397–2405. doi: 10.1002/eji.1830211016. [DOI] [PubMed] [Google Scholar]
  84. Schmidli J., Hunziker T., Moesli P., Schaad U. B. Cultivation of Borrelia burgdorferi from joint fluid three months after treatment of facial palsy due to Lyme borreliosis. J Infect Dis. 1988 Oct;158(4):905–906. doi: 10.1093/infdis/158.4.905. [DOI] [PubMed] [Google Scholar]
  85. Schmidt R., Kabatzki J., Hartung S., Ackermann R. Erythema-migrans-Borreliose in der Bundesrepublik Deutschland. Epidemiologie und klinisches Bild. Dtsch Med Wochenschr. 1985 Nov 22;110(47):1803–1807. doi: 10.1055/s-2008-1069091. [DOI] [PubMed] [Google Scholar]
  86. Schoen R. T., Aversa J. M., Rahn D. W., Steere A. C. Treatment of refractory chronic Lyme arthritis with arthroscopic synovectomy. Arthritis Rheum. 1991 Aug;34(8):1056–1060. doi: 10.1002/art.1780340817. [DOI] [PubMed] [Google Scholar]
  87. Schwartz I., Wormser G. P., Schwartz J. J., Cooper D., Weissensee P., Gazumyan A., Zimmermann E., Goldberg N. S., Bittker S., Campbell G. L. Diagnosis of early Lyme disease by polymerase chain reaction amplification and culture of skin biopsies from erythema migrans lesions. J Clin Microbiol. 1992 Dec;30(12):3082–3088. doi: 10.1128/jcm.30.12.3082-3088.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  88. Schwartz J. J., Gazumyan A., Schwartz I. rRNA gene organization in the Lyme disease spirochete, Borrelia burgdorferi. J Bacteriol. 1992 Jun;174(11):3757–3765. doi: 10.1128/jb.174.11.3757-3765.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  89. Shrestha M., Grodzicki R. L., Steere A. C. Diagnosing early Lyme disease. Am J Med. 1985 Feb;78(2):235–240. doi: 10.1016/0002-9343(85)90432-2. [DOI] [PubMed] [Google Scholar]
  90. Sköldenberg B., Stiernstedt G., Gårde A., Kolmodin G., Carlström A., Nord C. E. Chronic meningitis caused by a penicillin-sensitive microorganism? Lancet. 1983 Jul 9;2(8341):75–78. doi: 10.1016/s0140-6736(83)90061-2. [DOI] [PubMed] [Google Scholar]
  91. Stanek G., Klein J., Bittner R., Glogar D. Borrelia burgdorferi as an etiologic agent in chronic heart failure? Scand J Infect Dis Suppl. 1991;77:85–87. [PubMed] [Google Scholar]
  92. Stanek G., Klein J., Bittner R., Glogar D. Isolation of Borrelia burgdorferi from the myocardium of a patient with longstanding cardiomyopathy. N Engl J Med. 1990 Jan 25;322(4):249–252. doi: 10.1056/NEJM199001253220407. [DOI] [PubMed] [Google Scholar]
  93. Steere A. C., Batsford W. P., Weinberg M., Alexander J., Berger H. J., Wolfson S., Malawista S. E. Lyme carditis: cardiac abnormalities of Lyme disease. Ann Intern Med. 1980 Jul;93(1):8–16. doi: 10.7326/0003-4819-93-1-8. [DOI] [PubMed] [Google Scholar]
  94. Steere A. C., Duray P. H., Butcher E. C. Spirochetal antigens and lymphoid cell surface markers in Lyme synovitis. Comparison with rheumatoid synovium and tonsillar lymphoid tissue. Arthritis Rheum. 1988 Apr;31(4):487–495. doi: 10.1002/art.1780310405. [DOI] [PubMed] [Google Scholar]
  95. Steere A. C., Duray P. H., Butcher E. C. Spirochetal antigens and lymphoid cell surface markers in Lyme synovitis. Comparison with rheumatoid synovium and tonsillar lymphoid tissue. Arthritis Rheum. 1988 Apr;31(4):487–495. doi: 10.1002/art.1780310405. [DOI] [PubMed] [Google Scholar]
  96. Steere A. C., Dwyer E., Winchester R. Association of chronic Lyme arthritis with HLA-DR4 and HLA-DR2 alleles. N Engl J Med. 1990 Jul 26;323(4):219–223. doi: 10.1056/NEJM199007263230402. [DOI] [PubMed] [Google Scholar]
  97. Steere A. C., Dwyer E., Winchester R. Association of chronic Lyme arthritis with HLA-DR4 and HLA-DR2 alleles. N Engl J Med. 1990 Jul 26;323(4):219–223. doi: 10.1056/NEJM199007263230402. [DOI] [PubMed] [Google Scholar]
  98. Steere A. C. Lyme disease. N Engl J Med. 1989 Aug 31;321(9):586–596. doi: 10.1056/NEJM198908313210906. [DOI] [PubMed] [Google Scholar]
  99. Steere A. C. Lyme disease. N Engl J Med. 1989 Aug 31;321(9):586–596. doi: 10.1056/NEJM198908313210906. [DOI] [PubMed] [Google Scholar]
  100. Steere A. C., Malawista S. E., Bartenhagen N. H., Spieler P. N., Newman J. H., Rahn D. W., Hutchinson G. J., Green J., Snydman D. R., Taylor E. The clinical spectrum and treatment of Lyme disease. Yale J Biol Med. 1984 Jul-Aug;57(4):453–461. [PMC free article] [PubMed] [Google Scholar]
  101. Steere A. C., Malawista S. E., Hardin J. A., Ruddy S., Askenase W., Andiman W. A. Erythema chronicum migrans and Lyme arthritis. The enlarging clinical spectrum. Ann Intern Med. 1977 Jun;86(6):685–698. doi: 10.7326/0003-4819-86-6-685. [DOI] [PubMed] [Google Scholar]
  102. Steere A. C., Malawista S. E., Hardin J. A., Ruddy S., Askenase W., Andiman W. A. Erythema chronicum migrans and Lyme arthritis. The enlarging clinical spectrum. Ann Intern Med. 1977 Jun;86(6):685–698. doi: 10.7326/0003-4819-86-6-685. [DOI] [PubMed] [Google Scholar]
  103. Steere A. C., Malawista S. E., Newman J. H., Spieler P. N., Bartenhagen N. H. Antibiotic therapy in Lyme disease. Ann Intern Med. 1980 Jul;93(1):1–8. doi: 10.7326/0003-4819-93-1-1. [DOI] [PubMed] [Google Scholar]
  104. Steere A. C., Malawista S. E., Snydman D. R., Shope R. E., Andiman W. A., Ross M. R., Steele F. M. Lyme arthritis: an epidemic of oligoarticular arthritis in children and adults in three connecticut communities. Arthritis Rheum. 1977 Jan-Feb;20(1):7–17. doi: 10.1002/art.1780200102. [DOI] [PubMed] [Google Scholar]
  105. Steere A. C., Pachner A. R., Malawista S. E. Neurologic abnormalities of Lyme disease: successful treatment with high-dose intravenous penicillin. Ann Intern Med. 1983 Dec;99(6):767–772. doi: 10.7326/0003-4819-99-6-767. [DOI] [PubMed] [Google Scholar]
  106. Steere A. C., Schoen R. T., Taylor E. The clinical evolution of Lyme arthritis. Ann Intern Med. 1987 Nov;107(5):725–731. doi: 10.7326/0003-4819-107-5-725. [DOI] [PubMed] [Google Scholar]
  107. Stiernstedt G., Sköldenberg B., Gårde A., Kolmodin G., Jörbeck H., Svenungsson B., Carlström A. Clinical manifestations of Borrelia infections of the nervous system. Zentralbl Bakteriol Mikrobiol Hyg A. 1987 Feb;263(3):289–296. doi: 10.1016/s0176-6724(87)80079-2. [DOI] [PubMed] [Google Scholar]
  108. Stiernstedt G. Tick-borne Borrelia infection in Sweden. Scand J Infect Dis Suppl. 1985;45:1–70. doi: 10.3109/inf.1985.17.suppl-45.01. [DOI] [PubMed] [Google Scholar]
  109. Stiernstedt G. Tick-borne Borrelia infection in Sweden. Scand J Infect Dis Suppl. 1985;45:1–70. doi: 10.3109/inf.1985.17.suppl-45.01. [DOI] [PubMed] [Google Scholar]
  110. Szer I. S., Taylor E., Steere A. C. The long-term course of Lyme arthritis in children. N Engl J Med. 1991 Jul 18;325(3):159–163. doi: 10.1056/NEJM199107183250304. [DOI] [PubMed] [Google Scholar]
  111. Wilske B., Preac-Mursic V., Schierz G., Gueye W., Herzer P., Weber K. Immunochemische Analyse der Immunantwort bei Spätmanifestationen der Lyme Borreliose. Zentralbl Bakteriol Mikrobiol Hyg A. 1988 Mar;267(4):549–558. [PubMed] [Google Scholar]
  112. Wilske B., Preac-Mursic V., Schierz G., Gueye W., Herzer P., Weber K. Immunochemische Analyse der Immunantwort bei Spätmanifestationen der Lyme Borreliose. Zentralbl Bakteriol Mikrobiol Hyg A. 1988 Mar;267(4):549–558. [PubMed] [Google Scholar]
  113. Wilske B., Preac-Mursic V., Schierz G., Kühbeck R., Barbour A. G., Kramer M. Antigenic variability of Borrelia burgdorferi. Ann N Y Acad Sci. 1988;539:126–143. doi: 10.1111/j.1749-6632.1988.tb31846.x. [DOI] [PubMed] [Google Scholar]
  114. Yoshinari N. H., Reinhardt B. N., Steere A. C. T cell responses to polypeptide fractions of Borrelia burgdorferi in patients with Lyme arthritis. Arthritis Rheum. 1991 Jun;34(6):707–713. doi: 10.1002/art.1780340611. [DOI] [PubMed] [Google Scholar]
  115. Yssel H., Shanafelt M. C., Soderberg C., Schneider P. V., Anzola J., Peltz G. Borrelia burgdorferi activates a T helper type 1-like T cell subset in Lyme arthritis. J Exp Med. 1991 Sep 1;174(3):593–601. doi: 10.1084/jem.174.3.593. [DOI] [PMC free article] [PubMed] [Google Scholar]
  116. Zöller L., Burkard S., Schäfer H. Validity of western immunoblot band patterns in the serodiagnosis of Lyme borreliosis. J Clin Microbiol. 1991 Jan;29(1):174–182. doi: 10.1128/jcm.29.1.174-182.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
  117. Zöller L., Burkard S., Schäfer H. Validity of western immunoblot band patterns in the serodiagnosis of Lyme borreliosis. J Clin Microbiol. 1991 Jan;29(1):174–182. doi: 10.1128/jcm.29.1.174-182.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
  118. van der Linde M. R., Crijns H. J., Lie K. I. Transient complete AV block in Lyme disease. Electrophysiologic observations. Chest. 1989 Jul;96(1):219–221. doi: 10.1378/chest.96.1.219. [DOI] [PubMed] [Google Scholar]
  119. van der Linde M. R. Lyme carditis: clinical characteristics of 105 cases. Scand J Infect Dis Suppl. 1991;77:81–84. [PubMed] [Google Scholar]

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