Abstract
OBJECTIVES--To examine the relation between rheumatoid arthritis (RA) and bronchiectasis (BR). METHODS--Disease activity, outcome, extra-articular manifestations, and laboratory features were compared in 32 patients with BR and RA (RA-BR group), 32 matched patients with RA without BR (RA group), and 31 patients with BR but without arthritis (BR group). RESULTS--In 30 of the 32 (94%) patients with RA-BR, BR preceded RA. There was no functional or radiological difference between the RA-BR and RA groups, and except for xerophthalmia, which was more common in patients with RA-BR than patients with RA, there was no difference in extra-articular or laboratory features. CONCLUSIONS--Bronchiectasis does not lead to a more aggressive disease course in RA and, despite the recognised association, BR is not an extra-articular manifestation of rheumatoid disease.
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- ARONOFF A., BYWATERS E. G., FEARNLEY G. R. Lung lesions in rheumatoid arthritis. Br Med J. 1955 Jul 23;2(4933):228–232. doi: 10.1136/bmj.2.4933.228. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bamji A., Cooke N. Rheumatoid arthritis and chronic bronchial suppuration. Scand J Rheumatol. 1985;14(1):15–21. doi: 10.3109/03009748509102010. [DOI] [PubMed] [Google Scholar]
- Constantopoulos S. H., Papadimitriou C. S., Moutsopoulos H. M. Respiratory manifestations in primary Sjögren's syndrome. A clinical, functional, and histologic study. Chest. 1985 Aug;88(2):226–229. doi: 10.1378/chest.88.2.226. [DOI] [PubMed] [Google Scholar]
- Hilton A. M., Doyle L. Immunological abnormalities in bronchiectasis with chronic bronchial suppuration. Br J Dis Chest. 1978 Jul;72(3):207–216. doi: 10.1016/0007-0971(78)90043-8. [DOI] [PubMed] [Google Scholar]
- Kelly C., Gardiner P., Pal B., Griffiths I. Lung function in primary Sjögren's syndrome: a cross sectional and longitudinal study. Thorax. 1991 Mar;46(3):180–183. doi: 10.1136/thx.46.3.180. [DOI] [PMC free article] [PubMed] [Google Scholar]
- ROPES M. W., BENNETT G. A., COBB S., JACOX R., JESSAR R. A. 1958 Revision of diagnostic criteria for rheumatoid arthritis. Bull Rheum Dis. 1958 Dec;9(4):175–176. [PubMed] [Google Scholar]
- Radoux V., Ménard H. A., Bégin R., Décary F., Koopman W. J. Airways disease in rheumatoid arthritis patients. One element of a general exocrine dysfunction. Arthritis Rheum. 1987 Mar;30(3):249–256. doi: 10.1002/art.1780300302. [DOI] [PubMed] [Google Scholar]
- Solanki T., Neville E. Bronchiectasis and rheumatoid disease: is there an association? Br J Rheumatol. 1992 Oct;31(10):691–693. doi: 10.1093/rheumatology/31.10.691. [DOI] [PubMed] [Google Scholar]
- Wollheim F. A., Pettersson H., Saxne T., Sjöblom K. G. Radiographic assessment in relation to clinical and biochemical variables in rheumatoid arthritis. Scand J Rheumatol. 1988;17(6):445–453. doi: 10.3109/03009748809098805. [DOI] [PubMed] [Google Scholar]