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Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1994 Oct;53(10):695–698. doi: 10.1136/ard.53.10.695

Absence of Mycobacterium tuberculosis DNA in synovial fluid from patients with rheumatoid arthritis.

H Jalal 1, M Millar 1, C Linton 1, P Dieppe 1
PMCID: PMC1005439  PMID: 7979585

Abstract

OBJECTIVES--To determine whether Mycobacterium tuberculosis DNA can be detected in synovial fluid of patients with rheumatoid arthritis (RA). METHODS--The polymerase chain reaction was applied to cellular components of synovial fluid. RESULTS--No evidence of M tuberculosis DNA was found in synovial fluid from 31 patients with RA and 13 control patients. CONCLUSION--The findings do not support a role for persistent M tuberculosis infection in the pathogenesis of RA.

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Selected References

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