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Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1971 Sep;30(5):522–536. doi: 10.1136/ard.30.5.522

Lysosomal enzymes and inflammation with particular reference to rheumatoid diseases.

J Chayen, L Bitensky
PMCID: PMC1005818  PMID: 4329595

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Selected References

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  1. ALLISON A. C., MALLUCCI L. HISTOCHEMICAL STUDIES OF LYSOSOMES AND LYSOSOMAL ENZYMES IN VIRUS-INFECTED CELL CULTURES. J Exp Med. 1965 Mar 1;121:463–476. doi: 10.1084/jem.121.3.463. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Ali S. Y., Evans L., Stainthorpe E., Lack C. H. Characterization of cathepsins in cartilage. Biochem J. 1967 Nov;105(2):549–557. doi: 10.1042/bj1050549. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Ali S. Y. The degradation of cartilage matrix by an intracellular protease. Biochem J. 1964 Dec;93(3):611–618. doi: 10.1042/bj0930611. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Allison A. C., Magnus I. A., Young M. R. Role of lysosomes and of cell membranes in photosensitization. Nature. 1966 Feb 26;209(5026):874–878. doi: 10.1038/209874a0. [DOI] [PubMed] [Google Scholar]
  5. BARLAND P., NOVIKOFF A. B., HAMERMAN D. Electron microscopy of the human synovial membrane. J Cell Biol. 1962 Aug;14:207–220. doi: 10.1083/jcb.14.2.207. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. BERTHET J., DE DUVE C. Tissue fractionation studies. I. The existence of a mitochondria-linked, enzymically inactive form of acid phosphatase in rat-liver tissue. Biochem J. 1951 Dec;50(2):174–181. doi: 10.1042/bj0500174. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. BITENSKY L. CYTOTOXIC ACTION OF ANTIBODIES. Br Med Bull. 1963 Sep;19:241–244. doi: 10.1093/oxfordjournals.bmb.a070064. [DOI] [PubMed] [Google Scholar]
  8. Barrett A. J., Poole A. R. Unsuitability of leucine naphthylamide for the histochemical demonstration of lysosomal proteolytic activity. Nature. 1969 Oct 18;224(5216):279–280. doi: 10.1038/224279a0. [DOI] [PubMed] [Google Scholar]
  9. Behal F. J., Little G. H., Klein R. A. Arylamidase of human liver. Biochim Biophys Acta. 1969 Mar 18;178(1):118–127. doi: 10.1016/0005-2744(69)90138-7. [DOI] [PubMed] [Google Scholar]
  10. CANELLAKIS E. S., TUTTLE A. L., COHEN P. P. A comparative study of the end-products of uric acid oxidation by peroxidases. J Biol Chem. 1955 Mar;213(1):397–404. [PubMed] [Google Scholar]
  11. CASTOR C. W. The microscopic structure of normal human synovial tissue. Arthritis Rheum. 1960 Apr;3:140–151. doi: 10.1002/art.1780030205. [DOI] [PubMed] [Google Scholar]
  12. COCHRANE C. G., WEIGLE W. O., DIXON F. J. The role of polymorphonuclear leukocytes in the initiation and cessation of the Arthus vasculitis. J Exp Med. 1959 Sep 1;110:481–494. doi: 10.1084/jem.110.3.481. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. COHN Z. A., HIRSCH J. G. The isolation and properties of the specific cytoplasmic granules of rabbit polymorphonuclear leucocytes. J Exp Med. 1960 Dec 1;112:983–1004. doi: 10.1084/jem.112.6.983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Caygill J. C., Pitkeathly D. A. A study of beta-acetylglucosaminase and acid phosphatase in pathological joint fluids. Ann Rheum Dis. 1966 Mar;25(2):137–144. doi: 10.1136/ard.25.2.137. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Chayen J., Bitensky L., Butcher R. G., Cashman B. Evidence for altered lysosomal membranes in synovial lining cells from human rheumatoid joints. Beitr Pathol. 1971 Feb;142(2):137–149. [PubMed] [Google Scholar]
  16. Chayen J., Bitensky L., Poulter L. W. Histochemistry of some lysosomal "proteolytic" enzymes of human rheumatoid synovia. Nature. 1970 Mar 14;225(5237):1050–1051. doi: 10.1038/2251050a0. [DOI] [PubMed] [Google Scholar]
  17. DE DUVE C., PRESSMAN B. C., GIANETTO R., WATTIAUX R., APPELMANS F. Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue. Biochem J. 1955 Aug;60(4):604–617. doi: 10.1042/bj0600604. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. DESAI I. D., TAPPEL A. L. ERYTHROCYTE HEMOLYSIS BY ISOLATED RAT LIVER LYSOSOMES. Proc Soc Exp Biol Med. 1965 Feb;118:496–499. doi: 10.3181/00379727-118-29887. [DOI] [PubMed] [Google Scholar]
  19. DINGLE J. T. Aetiological factors in the collagen diseases. Lysosomal enzymes and the degradation of cartilage matrix. Proc R Soc Med. 1962 Feb;55:109–111. [PubMed] [Google Scholar]
  20. DUMONDE D. C., BITENSKY L., CUNNINGHAM G. J., CHAYEN J. THE EFFECTS OF ANTIBODIES ON CELLS. I. BIOCHEMICAL AND HISTOCHEMICAL EFFECTS OF ANTIBODIES AND COMPLEMENT ON ASCITES TUMOUR CELLS. Immunology. 1965 Jan;8:25–36. [PMC free article] [PubMed] [Google Scholar]
  21. DUMONDE D. C., GLYNN L. E. The production of arthritis in rabbits by an immunological reaction to fibrin. Br J Exp Pathol. 1962 Aug;43:373–383. [PMC free article] [PubMed] [Google Scholar]
  22. Dingle J. T., Fell H. B., Glauert A. M. Endocytosis of sugars in embryonic skeletal tissues in organ culture. IV. Lysosomal and other biochemical effects. General discussion. J Cell Sci. 1969 Jan;4(1):139–153. doi: 10.1242/jcs.4.1.139. [DOI] [PubMed] [Google Scholar]
  23. ESSNER E., NOVIKOFF A. B. Localization of acid phosphatase activity in hepatic lysosomes by means of electron microscopy. J Biophys Biochem Cytol. 1961 Apr;9:773–784. doi: 10.1083/jcb.9.4.773. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Eisen V. Kinin formation in human diseases. Sci Basis Med Annu Rev. 1969:146–165. [PubMed] [Google Scholar]
  25. Fell H. B. Role of biological membranes in some skeletal reactions. Ann Rheum Dis. 1969 May;28(3):213–227. doi: 10.1136/ard.28.3.213. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Ghadially F. N., Roy S. Ultrastructure of synovial membrane in rheumatoid arthritis. Ann Rheum Dis. 1967 Sep;26(5):426–443. doi: 10.1136/ard.26.5.426. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. HENDRY N. G., CARR A. J. A GLYCOSIDASE ABNORMALITY IN SYNOVIAL MEMBRANE IN JOINT DISEASE. Nature. 1963 Jul 27;199:392–392. doi: 10.1038/199392a0. [DOI] [PubMed] [Google Scholar]
  28. HIRSCH J. G., BERNHEIMER A. W., WEISSMANN G. MOTION PICTURE STUDY OF THE TOXIC ACTION OF STREPTOLYSINS ON LEUCOCYTES. J Exp Med. 1963 Aug 1;118:223–228. doi: 10.1084/jem.118.2.223. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. HOGEBOOM G. H., SCHNEIDER W. C., STRIEBICH M. J. Cytochemical studies. V. On the isolation and biochemical properties of liver cell nuclei. J Biol Chem. 1952 May;196(1):111–120. [PubMed] [Google Scholar]
  30. HOLLANDER J. L., MCCARTY D. J., Jr, ASTORGA G., CASTRO-MURILLO E. STUDIES ON THE PATHOGENESIS OF RHEUMATOID JOINT INFLAMMATION. I. THE "R.A. CELL" AND A WORKING HYPOTHESIS. Ann Intern Med. 1965 Feb;62:271–280. doi: 10.7326/0003-4819-62-2-271. [DOI] [PubMed] [Google Scholar]
  31. HOLTER H. Pinocytosis. Int Rev Cytol. 1959;8:481–504. doi: 10.1016/s0074-7696(08)62738-2. [DOI] [PubMed] [Google Scholar]
  32. HOWELL R. R., SEEGMILLER J. E. Uricolysis by human leukocytes. Nature. 1962 Nov 3;196:482–483. doi: 10.1038/196482a0. [DOI] [PubMed] [Google Scholar]
  33. JACOX R. F., FELDMAHN A. Variations of beta glucuronidase concentration in abnormal human synovial fluid. J Clin Invest. 1955 Feb;34(2):263–267. doi: 10.1172/JCI103079. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. JANOFF A., ZWEIFACH B. W. PRODUCTION OF INFLAMMATORY CHANGES IN THE MICROCIRCULATION BY CATIONIC PROTEINS EXTRACTED FROM LYSOSOMES. J Exp Med. 1964 Nov 1;120:747–764. doi: 10.1084/jem.120.5.747. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. Janoff A., Scherer J. Mediators of inflammation in leukocyte lysosomes. IX. Elastinolytic activity in granules of human polymorphonuclear leukocytes. J Exp Med. 1968 Nov 1;128(5):1137–1155. doi: 10.1084/jem.128.5.1137. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. KELLERMEYER R. W., BRECKENRIDGE R. T. THE INFLAMMATORY PROCESS IN ACUTE GOUTY ARTHRITIS. I. ACTIVATION OF HAGEMAN FACTOR BY SODIUM URATE CRYSTALS. J Lab Clin Med. 1965 Feb;65:307–315. [PubMed] [Google Scholar]
  37. LACK C. H., ALI S. Y. TISSUE ACTIVATOR OF PLASMINOGEN. Nature. 1964 Mar 7;201:1030–1031. doi: 10.1038/2011030a0. [DOI] [PubMed] [Google Scholar]
  38. LEHMAN M. A., KREAM J., BROGNA D. ACID AND ALKALINE PHOSPHATASE ACTIVITY IN THE SERUM AND SYNOVIAL FLUID OF PATIENTS WITH ARTHRITIS. J Bone Joint Surg Am. 1964 Dec;46:1732–1738. [PubMed] [Google Scholar]
  39. LUSCOMBE M. Acid phosphatase and catheptic activity in rheumatoid synovial tissue. Nature. 1963 Mar 9;197:1010–1010. doi: 10.1038/1971010a0. [DOI] [PubMed] [Google Scholar]
  40. Lorber A., Cutler L. S., Chang C. C. Serum copper levels in rheumatoid arthritis: relationship of elevated copper to protein alterations. Arthritis Rheum. 1968 Feb;11(1):65–71. doi: 10.1002/art.1780110109. [DOI] [PubMed] [Google Scholar]
  41. Lucy J. A., Lichti F. U. Reactions of vitamin A with acceptors of electrons. Interactions with iodine and the formation of iodide. Biochem J. 1969 Apr;112(2):231–241. doi: 10.1042/bj1120231. [DOI] [PMC free article] [PubMed] [Google Scholar]
  42. MOVAT H. Z., URIUHARA T., MACMORINE D. L., BURKE J. S. A PERMEABILITY FACTOR RELEASED FROM LEUKOCYTES AFTER PHAGOCYTOSIS OF IMMUNE COMPLEXES AND ITS POSSIBLE ROLE IN THE ARTHUS REACTION. Life Sci. 1964 Sep;3:1025–1032. doi: 10.1016/0024-3205(64)90115-8. [DOI] [PubMed] [Google Scholar]
  43. Mahadevan S., Tappel A. L. Arylamidases of rat liver and kidney. J Biol Chem. 1967 May 25;242(10):2369–2374. [PubMed] [Google Scholar]
  44. Marks N., Datta R. K., Lajtha A. Partial resolution of brain arylamidases and aminopeptidases. J Biol Chem. 1968 Jun 10;243(11):2882–2889. [PubMed] [Google Scholar]
  45. McDonald J. K., Reilly T. J., Zeitman B. B., Ellis S. Dipeptidyl arylamidase II of the pituitary. Properties of lysylalanyl-beta-naphthylamide hydrolysis: inhibition by cations, distribution in tissues, and subcellular localization. J Biol Chem. 1968 Apr 25;243(8):2028–2037. [PubMed] [Google Scholar]
  46. Melmon K. L., Webster M. E., Goldfinger S. E., Seegmiller J. E. The presence of a kinin in inflammatory synovial effusion from arthritides of varying etiologies. Arthritis Rheum. 1967 Feb;10(1):13–20. doi: 10.1002/art.1780100103. [DOI] [PubMed] [Google Scholar]
  47. NOVIKOFF A. B., BEAUFAY H., DE DUVE C. Electron microscopy of lysosomerich fractions from rat liver. J Biophys Biochem Cytol. 1956 Jul 25;2(4 Suppl):179–184. [PMC free article] [PubMed] [Google Scholar]
  48. Persellin R. H., Ziff M. The effect of gold salt on lysosomal enzymes of the peritoneal macrophage. Arthritis Rheum. 1966 Feb;9(1):57–65. doi: 10.1002/art.1780090107. [DOI] [PubMed] [Google Scholar]
  49. Phelps P., McCarty D. J., Jr Crystal-induced inflammation in canine joints. II. Importance of polymorphonuclear leukocytes. J Exp Med. 1966 Jul 1;124(1):115–126. doi: 10.1084/jem.124.1.115. [DOI] [PMC free article] [PubMed] [Google Scholar]
  50. Poulter L. W., Bitensky L., Cashman B., Chayen J. The maintenance of human synovial tissue in vitro. Virchows Arch B Cell Pathol. 1970;4(4):303–309. [PubMed] [Google Scholar]
  51. RAWSON A. J., ABELSON N. M., HOLLANDER J. L. STUDIES ON THE PATHOGENESIS OF RHEUMATOID JOINT INFLAMMATION. II. INTRACYTOPLASMIC PARTICULATE COMPLEXES IN RHEUMATOID SYNOVIAL FLUIDS. Ann Intern Med. 1965 Feb;62:281–284. doi: 10.7326/0003-4819-62-2-281. [DOI] [PubMed] [Google Scholar]
  52. RESTIFO R. A., LUSSIER A. J., RAWSON A. J., ROCKEY J. H., HOLLANDER J. L. STUDIES ON THE PATHOGENESIS OF RHEUMATOID JOINT INFLAMMATION. 3. THE EXPERIMENTAL PRODUCTION OF ARTHRITIS BY THE INTRA-ARTICULAR INJECTION OF PURIFIED 7S GAMMA GLOBULIN. Ann Intern Med. 1965 Feb;62:285–291. doi: 10.7326/0003-4819-62-2-285. [DOI] [PubMed] [Google Scholar]
  53. Rajan K. T. Lysosomes and gout. Nature. 1966 May 28;210(5039):959–960. doi: 10.1038/210959a0. [DOI] [PubMed] [Google Scholar]
  54. SCHULTZ J., KAMINKER K. Myeloperoxidase of the leucocyte of normal human blood. I. Content and localization. Arch Biochem Biophys. 1962 Mar;96:465–467. doi: 10.1016/0003-9861(62)90321-1. [DOI] [PubMed] [Google Scholar]
  55. SEEGMILLER J. E., HOWELL R. R. The old and new concepts of acute gouty arthritis. Arthritis Rheum. 1962 Dec;5:616–623. doi: 10.1002/art.1780050610. [DOI] [PubMed] [Google Scholar]
  56. STRAUS W. Colorimetric analysis with N, N-dimethyl-p-phenylenediamine of the uptake of intravenously injected horseradish peroxidase by various tissues of the rat. J Biophys Biochem Cytol. 1958 Sep 25;4(5):541–550. doi: 10.1083/jcb.4.5.541. [DOI] [PMC free article] [PubMed] [Google Scholar]
  57. Slater T. F., Riley P. A. Photosensitization and lysosomal damage. Nature. 1966 Jan 8;209(5019):151–154. doi: 10.1038/209151a0. [DOI] [PubMed] [Google Scholar]
  58. Snellman O. Cathepsin B, the lysosomal thiol proteinase of calf liver. Biochem J. 1969 Oct;114(4):673–678. doi: 10.1042/bj1140673b. [DOI] [PMC free article] [PubMed] [Google Scholar]
  59. UHR J. W. THE HETEROGENEITY OF THE IMMUNE RESPONSE. Science. 1964 Jul 31;145(3631):457–464. doi: 10.1126/science.145.3631.457. [DOI] [PubMed] [Google Scholar]
  60. WEISSMANN G., BECHER B., WIEDERMANN G., BERNHEIMER A. W. STUDIES ON LYSOSOMES. VII. ACUTE AND CHRONIC ARTHRITIS PRODUCED BY INTRA-ARTICULAR INJECTIONS OF STREPTOLYSIN S IN RABBITS. Am J Pathol. 1965 Jan;46:129–147. [PMC free article] [PubMed] [Google Scholar]
  61. WEISSMANN G. LYSOSOMES, AUTOIMMUNE PHENOMENA, AND DISEASES OF CONNECTIVE TISSUE. Lancet. 1964 Dec 26;2(7374):1373–1375. doi: 10.1016/s0140-6736(64)91163-8. [DOI] [PubMed] [Google Scholar]
  62. WOODIN A. M., FRENCH J. E., MARCHESI V. T. Morphological changes associated with the extrusion of protein induced in the polymorphonuclear leucocyte by staphylococcal leucocidin. Biochem J. 1963 Jun;87:567–571. doi: 10.1042/bj0870567. [DOI] [PMC free article] [PubMed] [Google Scholar]
  63. Watts R. W., Scott J. T., Chalmers R. A., Bitensky L., Chayen J. Microscopic studies on skeletal muscle in gout patients treated with allopurinol. Q J Med. 1971 Jan;40(157):1–14. [PubMed] [Google Scholar]
  64. Weissmann G., Spilberg I. Breakdown of cartilage proteinpolysaccharide by lysosomes. Arthritis Rheum. 1968 Apr;11(2):162–169. doi: 10.1002/art.1780110206. [DOI] [PubMed] [Google Scholar]
  65. Weissmann G., Spilberg I., Krakauer K. Arthritis induced in rabbits by lysates of granulocyte lysosomes. Arthritis Rheum. 1969 Apr;12(2):103–116. doi: 10.1002/art.1780120207. [DOI] [PubMed] [Google Scholar]
  66. Weston P. D., Barrett A. J., Dingle J. T. Specific inhibition of cartilage breakdown. Nature. 1969 Apr 19;222(5190):285–286. doi: 10.1038/222285b0. [DOI] [PubMed] [Google Scholar]
  67. Wyllie J. C., Haust M. D., More R. H. The fine structure of synovial lining cells in rheumatoid arthritis. Lab Invest. 1966 Mar;15(3):519–529. [PubMed] [Google Scholar]
  68. ZUCKER-FRANKLIN D., HIRSCH J. G. ELECTRON MICROSCOPE STUDIES ON THE DEGRANULATION OF RABBIT PERITONEAL LEUKOCYTES DURING PHAGOCYTOSIS. J Exp Med. 1964 Oct 1;120:569–576. doi: 10.1084/jem.120.4.569. [DOI] [PMC free article] [PubMed] [Google Scholar]
  69. Zucker-Franklin D. The phagosomes in rheumatoid synovial fluid leukocytes: a light, fluorescence, and electron microscope study. Arthritis Rheum. 1966 Feb;9(1):24–36. doi: 10.1002/art.1780090104. [DOI] [PubMed] [Google Scholar]

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