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Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1988 Aug;47(8):642–644. doi: 10.1136/ard.47.8.642

Induction of antinuclear antibodies in patients with rheumatoid arthritis receiving treatment with human recombinant interferon gamma.

M Seitz 1, M Franke 1, H Kirchner 1
PMCID: PMC1006714  PMID: 3137901

Abstract

Of six patients with rheumatoid arthritis (RA) treated with human recombinant interferon gamma for two to eight months, three developed antinuclear antibodies (ANAs). This was accompanied by a simultaneous clinical exacerbation of the disease activity. In this study both anti-inflammatory and immunostimulatory effects of human recombinant interferon gamma in patients with RA were observed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bottazzo G. F., Pujol-Borrell R., Hanafusa T., Feldmann M. Role of aberrant HLA-DR expression and antigen presentation in induction of endocrine autoimmunity. Lancet. 1983 Nov 12;2(8359):1115–1119. doi: 10.1016/s0140-6736(83)90629-3. [DOI] [PubMed] [Google Scholar]
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