Abstract
The risk of an asbestos worker developing small irregular opacities on the chest radiograph is related to cumulative exposure to asbestos dust, latency, and smoking habit. In this study the use of residence-time weighted exposure as a "dose metric" was explored in a cohort of asbestos cement workers. It was found that this parameter, which incorporates both exposure concentration and latency, is useful for modelling the risk of small opacities and might also be useful for modelling the risk of mesothelioma.
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Selected References
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- Berry G., Gilson J. C., Holmes S., Lewinsohn H. C., Roach S. A. Asbestosis: a study of dose-response relationships in an asbestos textile factory. Br J Ind Med. 1979 May;36(2):98–112. doi: 10.1136/oem.36.2.98. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Finkelstein M. M. Asbestosis in long-term employees of an Ontario asbestos-cement factory. Am Rev Respir Dis. 1982 May;125(5):496–501. doi: 10.1164/arrd.1982.125.5.496. [DOI] [PubMed] [Google Scholar]
- Finkelstein M. M., Vingilis J. J. Radiographic abnormalities among asbestos-cement workers. An exposure-response study. Am Rev Respir Dis. 1984 Jan;129(1):17–22. doi: 10.1164/arrd.1984.129.1.17. [DOI] [PubMed] [Google Scholar]
- Jahr J. Dose-response basis for settling a quartz threshold limit value: a new, simple formula for calculating the "lifetime dose" of quartz. Arch Environ Health. 1974 Dec;29(6):338–340. doi: 10.1080/00039896.1974.10666611. [DOI] [PubMed] [Google Scholar]
- Liddell F. D., Gibbs G. W., McDonald J. C. Radiological changes and fibre exposure in chrysotile workers aged 60-69 years at Thetford Mines. Ann Occup Hyg. 1982;26(1-4):889–898. [PubMed] [Google Scholar]
- Peto J., Seidman H., Selikoff I. J. Mesothelioma mortality in asbestos workers: implications for models of carcinogenesis and risk assessment. Br J Cancer. 1982 Jan;45(1):124–135. doi: 10.1038/bjc.1982.15. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Thomas D. G., Breslow N., Gart J. J. Trend and homogeneity analyses of proportions and life table data. Comput Biomed Res. 1977 Aug;10(4):373–381. doi: 10.1016/0010-4809(77)90006-4. [DOI] [PubMed] [Google Scholar]
- Viallat J. R., Boutin C., Pietri J. F., Fondarai J. Late progression of radiographic changes in Canari chrysotile mine and mill exworkers. Arch Environ Health. 1983 Jan-Feb;38(1):54–58. doi: 10.1080/00039896.1983.10543979. [DOI] [PubMed] [Google Scholar]