Abstract
Mortality was updated to the end of 1982 for 594 employees exposed to benzene who had been studied previously and for an additional 362 exposed workers not studied previously. Cause specific mortality comparisons were made using United States white male, age, and calendar year adjusted rates. Total mortality was observed to have been significantly below expectation, and this was particularly evident for deaths from accidental causes. Mortality from skin cancer was significantly raised, although there were no unusual or common characteristics among the affected individuals which would suggest a link with exposure to benzene. A non-significant excess of total deaths from leukaemia was noted based on four observed cases; however, all four were myelogenous leukaemias and this represented a significant excess in that subcategory. These and other deaths of possible interest are reviewed in detail. Analyses by work area, duration of exposure, and cumulative dose index did not show patterns suggestive of a causal association between exposure to benzene and any particular cause of death.
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Selected References
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- Aksoy M. Malignancies due to occupational exposure to benzene. Am J Ind Med. 1985;7(5-6):395–402. doi: 10.1002/ajim.4700070506. [DOI] [PubMed] [Google Scholar]
- Decouflé P., Blattner W. A., Blair A. Mortality among chemical workers exposed to benzene and other agents. Environ Res. 1983 Feb;30(1):16–25. doi: 10.1016/0013-9351(83)90161-5. [DOI] [PubMed] [Google Scholar]
- Infante P. F., White M. C. Projections of leukemia risk associated with occupational exposure to benzene. Am J Ind Med. 1985;7(5-6):403–413. doi: 10.1002/ajim.4700070507. [DOI] [PubMed] [Google Scholar]
- Monson R. R. Analysis of relative survival and proportional mortality. Comput Biomed Res. 1974 Aug;7(4):325–332. doi: 10.1016/0010-4809(74)90010-x. [DOI] [PubMed] [Google Scholar]
- Ott M. G., Holder B. B., Gordon H. L. Respiratory cancer and occupational exposure to arsenicals. Arch Environ Health. 1974 Nov;29(5):250–255. doi: 10.1080/00039896.1974.10666582. [DOI] [PubMed] [Google Scholar]
- Ott M. G., Langer R. R., Holder B. B. Vinyl chloride exposure in a controlled industrial environment. A long-term mortality experience in 594 employees. Arch Environ Health. 1975 Jul;30(7):333–339. doi: 10.1080/00039896.1975.10666716. [DOI] [PubMed] [Google Scholar]
- Ott M. G., Townsend J. C., Fishbeck W. A., Langner R. A. Mortality among individuals occupationally exposed to benzene. Arch Environ Health. 1978 Jan-Feb;33(1):3–10. doi: 10.1080/00039896.1978.10667299. [DOI] [PubMed] [Google Scholar]