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British Journal of Industrial Medicine logoLink to British Journal of Industrial Medicine
. 1978 Feb;35(1):1–7. doi: 10.1136/oem.35.1.1

In vivo observations of skin capillaries in workers exposed to vinyl chloride. An English-American comparison.

H R Maricq, C S Darke, R M Archibald, E C Leroy
PMCID: PMC1008316  PMID: 629883

Abstract

An unselected sample of vinyl chloride (VC)-exposed individuals, all employees of a polyvinyl chloride production plant in England (129 subjects), were examined by in vivo capillary microscopy. Results were compared with those previously obtained from a similar study in the USA to determine whether an association between VC exposure and capillary abnormalities could be found in different environments. The results showed a similar distribution of capillary abnormalities among the VC workers in both countries (39.5% in England compared with 36% in the USA). These capillary abnormalities were significantly more frequent among VC-exposed subjects than among control industrial workers (7.7%, 6%). In vivo microscopy also showed a higher incidence of papular lesions (13.5%) than had been detected clinically (1%).

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Selected References

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